Yang Bi-Sui, Huang Qiu-Lian, Xie Lu-Xin, Wu Bo, Deng Ke-Zhong, Wu Zhi-Gui, Zhu Wei-Feng, He Shao-Lang, Huang Qi, Zhu Yu-Ye, Ge Fei
School of Pharmacy, Jiangxi University of Traditional Chinese Medicine Nanchang 330004, China.
Jiangxi Institute of Red Soil Nanchang 330046, China.
Zhongguo Zhong Yao Za Zhi. 2021 May;46(9):2149-2157. doi: 10.19540/j.cnki.cjcmm.20210225.102.
Molecular pharmacognosy is a science of classification and identification, cultivation and protection, and production of active ingredients of graduated drugs at the molecular level. The proposal of molecular pharmacognosy allows the research of crude drugs to advance from the microscopic level to the genetic level. Pueraria lobata root, as a medicinal and edible plant, has high application value and economic value. There are many varieties that are easy to cause confusion, and it is not easy to distinguish and identify according to traditional identification methods. Moreover, the research of P. lobate root at the genetic level is still relatively shallow. the study received extensive attention of scholars. This article reviews recent research on molecular identification of P. lobate, transcriptome sequencing, cloning and synthesis of functional genes of P. lobate root in recent years in order to provide references for further promoting the development and utilization of P. lobate root and its active ingredients.
分子生药学是一门在分子水平上对中药材进行分类鉴定、栽培保护及活性成分生产的科学。分子生药学的提出使中药材研究从微观层面深入到基因水平。葛根作为药食两用植物，具有较高的应用价值和经济价值。其品种繁多，易造成混淆，按传统鉴别方法不易区分识别。此外，葛根在基因水平上的研究仍相对薄弱。该研究受到了学者们的广泛关注。本文综述了近年来葛根分子鉴定、转录组测序以及葛根功能基因克隆与合成等方面的研究进展，以期为进一步推动葛根及其活性成分的开发利用提供参考。
