University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA, United States.
University of Houston, Department of Psychology, Houston, TX, United States; University of Houston, Texas Institute for Measurement, Evaluation, and Statistics, Houston, TX, United States.
Behav Res Ther. 2021 Jul;142:103861. doi: 10.1016/j.brat.2021.103861. Epub 2021 Apr 18.
The conditions and populations for which anxiety sensitivity (AS; i.e., the tendency to interpret unpleasant physiological sensations as dangerous) relates to adolescent alcohol use is unclear. This study tested latent-variable cross-lagged panel modeling of AS-alcohol relations in a racially/ethnically heterogenous longitudinal youth cohort (N = 3396; 53.4% female, 45.8% Latinx) assessed annually across high school. Anxiety and race/ethnicity were tested as mediators and moderators, respectively, of AS-alcohol associations. AS prospectively predicted alcohol problems (β's = 0.05-0.07) but not alcohol consumption (β's = 0.02-0.04) across high school. Alcohol problems predicted AS at the end (β = 0.09) but not beginning (β's = 0.01-0.03) of high school and alcohol consumption predicted lower AS at the beginning (β = -0.06) but not end (β's = -0.02-0.01) of high school. Anxiety mediated AS's predictive effects on alcohol problems (β's = 0.01, 95% CI [0.003, 0.03]) across high school. Race/ethnicity did not moderate interrelations of AS, anxiety, and alcohol outcomes. These findings lend support to the risk factor model of AS on alcohol problems (but not consumption) through anxiety and the scar/complication model whereby alcohol problems may exacerbate AS later in adolescence. Addressing reciprocal risk processes between AS, anxiety, and alcohol problems warrant consideration in adolescent behavioral health promotion for various racial/ethnic populations.
焦虑敏感（AS；即，将不愉快的生理感觉解释为危险的倾向）与青少年饮酒之间的关系的条件和人群尚不清楚。本研究在一个种族/民族多样化的纵向青年队列（N=3396；53.4%女性，45.8%拉丁裔）中测试了 AS-酒精关系的潜在变量交叉滞后面板模型，该队列在整个高中阶段每年进行评估。焦虑和种族/民族分别作为 AS-酒精关联的中介和调节因素进行了测试。AS 前瞻性地预测了高中阶段的酒精问题（β's=0.05-0.07），但未预测酒精消耗（β's=0.02-0.04）。高中结束时，酒精问题预测了 AS（β=0.09），但高中开始时没有（β's=0.01-0.03），而酒精消耗预测了 AS 的开始（β=-0.06），但高中结束时没有（β's=-0.02-0.01）。焦虑在整个高中阶段中介了 AS 对酒精问题的预测作用（β's=0.01，95%CI[0.003，0.03]）。种族/民族并没有调节 AS、焦虑和酒精结果之间的相互关系。这些发现支持了 AS 对酒精问题（但不是对酒精消耗）的风险因素模型，以及酒精问题可能会在青春期后期加剧 AS 的疤痕/并发症模型。在青少年行为健康促进中，需要考虑针对不同种族/民族群体的 AS、焦虑和酒精问题之间的相互风险过程。
