Kepka A G, Johnson P M, Kline R W
Department of Radiology, Northwestern University, Northwestern Memorial Hospital, Chicago, Illinois 60611.
Med Phys. 1988 May-Jun;15(3):375-9. doi: 10.1118/1.596234.
A calculation is described that enables the rapid assessment of dose rate at various points of interest within the eye (lens, optic nerve, etc.) for the treatment of choroidal melanoma by plaque therapy. 125I seeds are used as the radiation source. The location of the plaque and its associated seeds relative to the eye (in a Cartesian coordinate system) is determined from the description of the tumor, as drawn and dimensioned on a fundus-view diagram by the ophthalmologist. This requires a computer to numerically solve an equation, which is derived in the framework of spherical geometry. Further results of this calculation yield data files that serve as the input to a conventional brachytherapy treatment planning program. This enables the visualization of the dose distribution within a plane that contains the major axis of the tumor in order to assess the adequacy of the treated volume.
本文描述了一种计算方法，可用于通过敷贴疗法治疗脉络膜黑色素瘤时，快速评估眼内各感兴趣点（晶状体、视神经等）的剂量率。使用¹²⁵I种子作为辐射源。根据眼科医生在眼底视图图上绘制并标注尺寸的肿瘤描述，确定敷贴及其相关种子相对于眼睛的位置（在笛卡尔坐标系中）。这需要计算机对一个在球面几何框架下推导出来的方程进行数值求解。该计算的进一步结果生成数据文件，作为传统近距离放射治疗治疗计划程序的输入。这能够在包含肿瘤长轴的平面内可视化剂量分布，以便评估治疗体积是否足够。
