AP-HP, Centre Hospitalier Universitaire de Colombes, Hôpital Louis Mourier, Colombes, France; INSERM UMRS1266, Institute of Psychiatry and Neurosciences of Paris, Paris, France.
INSERM UMRS1266, Institute of Psychiatry and Neurosciences of Paris, Paris, France.
Conscious Cogn. 2021 Aug;93:103154. doi: 10.1016/j.concog.2021.103154. Epub 2021 May 27.
The moving rubber hand illusion allows the evaluation both the sense of body ownership and agency using visuo-motor stimulations.
We used the moving rubber hand illusion in anatomic congruence with explicit measures to compare active asynchronous and passive synchronous movements in patients diagnosed with schizophrenia with first rank symptoms (FRS) (n = 31) versus without FRS (n = 25).
Patients with FRS are characterized by a lack of agency in active asynchronous condition. The two groups had no sense of ownership in synchronous passive condition. Using a multivariate regression model, we found an association between agency and body ownership measures in the active asynchronous condition in two groups (OR: 1.825, p < 0.001). In the passive condition, this association was only present in the group with first rank symptoms (OR: 2.04, p < 0.001).
Temporal proximity and sensorimotor information are essential in the understanding of self-consciousness disorders in schizophrenia.
移动橡胶手错觉允许使用视动刺激来评估身体所有权和主体感。
我们使用与解剖学一致的移动橡胶手错觉，并采用明确的测量方法，比较了具有一级症状（FRS）的精神分裂症患者（n=31）与无 FRS 的患者（n=25）的主动异步和被动同步运动。
具有 FRS 的患者在主动异步条件下表现出缺乏主体感。两组在同步被动条件下都没有拥有感。使用多元回归模型，我们在两组的主动异步条件下发现了主体感和主体感测量之间的关联（OR：1.825，p<0.001）。在被动条件下，这种关联仅存在于具有一级症状的组中（OR：2.04，p<0.001）。
时间接近和感觉运动信息是理解精神分裂症中自我意识障碍的关键。
