Kim Su Jin, Kim Jayoung, Na Yong Gil, Kim Khae Hawn
Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea.
Departments of Surgery and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Int Neurourol J. 2021 May;25(Suppl 1):S3-7. doi: 10.5213/inj.2142174.087. Epub 2021 May 31.
Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is regarded as an important mechanism associated with bladder fibrosis. However, various risk factors and conditions contribute to the functional impairment of the bladder associated with fibrosis, and there is limited knowledge about bladder fibrosis-associated problems in the field of neurourology. Further studies are thus necessary to elucidate the underlying mechanism of bladder fibrosis and to identify effective treatment.
膀胱活动低下和膀胱顺应性受损是与膀胱纤维化相关的不可逆问题。细胞外基质重塑被认为是与膀胱纤维化相关的重要机制。然而，多种风险因素和状况会导致与纤维化相关的膀胱功能损害，并且在神经泌尿学领域，关于膀胱纤维化相关问题的了解有限。因此，有必要进一步研究以阐明膀胱纤维化的潜在机制并确定有效的治疗方法。
