圆锥角膜的角膜交联术：视网膜和脉络膜的评估
Corneal cross-linking for keratoconus: Evaluation of the retina and choroid.
作者信息
Nasrollahi Kobra, Razmjoo Fatemeh, Naderan Morteza, Peyman Alireza
机构信息
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Eur J Ophthalmol. 2022 May;32(3):1491-1495. doi: 10.1177/11206721211021300. Epub 2021 May 31.
PURPOSE
To investigate the possible structural changes of the central choroid and retina after collagen cross-linking (CXL) in patients with progressive keratoconus (KCN).
METHODS
Twenty-five eyes of 25 patients were included in this study. Patients underwent enhanced depth imaging optical coherence tomography (EDI-OCT) before and 1 month after CXL. The values for central macular thickness (CMT), subfoveal choroidal thickness (CHT), and choroidal volume (CHV) were evaluated.
RESULTS
CMT before and after CXL was 263.24 ± 16.25 μm and 263.20 ± 16.51 μm, respectively ( = 0.98). CHT was 362.08 ± 36.80 μm and 367.84 ± 33.67 μm before and after CXL, respectively ( = 0.26). CHV was 8.74 ± 0.33 mm3 and 8.68 ± 0.36 mm3 before and after CXL, respectively ( = 0.11). There was no significant difference in the corrected distance visual acuity before and after CXL (0.06 ± 0.05 and 0.05 ± 0.05 logMAR, respectively, = 0.65).
CONCLUSION
Central retinal and choroidal thicknesses are not changed after corneal cross- linking.
目的
研究进行性圆锥角膜（KCN）患者胶原交联（CXL）后中央脉络膜和视网膜可能的结构变化。
方法
本研究纳入25例患者的25只眼。患者在CXL术前及术后1个月接受增强深度成像光学相干断层扫描（EDI-OCT）检查。评估中央黄斑厚度（CMT）、黄斑中心凹下脉络膜厚度（CHT）和脉络膜体积（CHV）的值。
结果
CXL术前及术后的CMT分别为263.24±16.25μm和263.20±16.51μm（P = 0.98）。CXL术前及术后的CHT分别为362.08±36.80μm和367.84±33.67μm（P = 0.26）。CXL术前及术后的CHV分别为8.74±0.33mm³和8.68±0.36mm³（P = 0.11）。CXL术前及术后的矫正远视力无显著差异（分别为0.06±0.05和0.05±0.05 logMAR，P = 0.65）。
结论
角膜交联后中央视网膜和脉络膜厚度未发生改变。
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