Radiation Medicine Program, Princess Margaret Cancer Center, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada; Department of Radiation Oncology Temerty Faculty of Medicine, University of Toronto, 149 College Street, Suite 504, Toronto, ON M5T 1P5, Canada.
Joint Department Medical Imaging, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Suite 3-920, Toronto, ON M5G 2M9, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON M5T 1W7, Canada.
PET Clin. 2021 Jul;16(3):353-364. doi: 10.1016/j.cpet.2021.03.002.
This article summarizes the role of PET imaging for detection, characterization, and theranostic/therapy planning for neuroendocrine tumors. Topics in this article span overall imaging accuracy with mostly Ga-DOTA-peptide imaging as well as basic principles of individualized dosimetry. There is also some discussion around further specialized approaches in dosimetry in theranostics. In addition, an overview of the literature on functional imaging in neuroendocrine tumors and the current understanding of imaging-derived clinical outcome prediction are presented.
本文总结了 PET 成像在神经内分泌肿瘤的检测、特征描述、以及治疗/治疗计划中的作用。本文涵盖了整体成像准确性,主要是 Ga-DOTA-肽成像以及个体化剂量学的基本原理。还讨论了治疗中剂量学的进一步专门方法。此外,还对神经内分泌肿瘤的功能成像文献进行了概述,并介绍了目前对成像衍生临床结果预测的理解。