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社会地理因素与多发性硬化症——一项在6个欧洲国家开展的生态学研究

Sociogeographic factors and multiple sclerosis--an ecological study in 6 European countries.

作者信息

Lauer K

机构信息

Department of Neurology, Academic Teaching Hospital, Darmstadt, FRG.

出版信息

Neuroepidemiology. 1988;7(3):122-9. doi: 10.1159/000110145.

DOI:10.1159/000110145
PMID:3405364
Abstract

The pattern of the multiple sclerosis (MS) risk in Norway, Denmark, Sweden, Switzerland, Finland and Holland, as reported in previous studies, was compared with the distribution of several sociogeographic factors. For none of the variables tested did an association with MS exist in all of these countries. A correlation in more than one country was found for the proportion of industrial workers in the total population and for the extent of oat cultivation. Arguments against a causal role of these factors as such exist, however, and are discussed. For a number of other variables that might be implicated in the context of prior findings or suggestions either no or only an inconsistent association with MS was found.

摘要

以往研究报告了挪威、丹麦、瑞典、瑞士、芬兰和荷兰的多发性硬化症(MS)风险模式,并将其与几个社会地理因素的分布进行了比较。在所有这些国家中,所测试的变量均未与MS存在关联。在总人口中产业工人的比例以及燕麦种植范围这两个变量上,发现有不止一个国家存在相关性。然而,存在反对这些因素本身具有因果作用的观点,并对此进行了讨论。对于其他一些可能与先前研究结果或建议相关的变量,要么未发现与MS有联系,要么发现的联系并不一致。

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Sociogeographic factors and multiple sclerosis--an ecological study in 6 European countries.社会地理因素与多发性硬化症——一项在6个欧洲国家开展的生态学研究
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Environmental associations with the risk of multiple sclerosis: the contribution of ecological studies.环境因素与多发性硬化症风险的关联:生态学研究的贡献
Acta Neurol Scand Suppl. 1995;161(Suppl 161):77-88. doi: 10.1111/j.1600-0404.1995.tb05861.x.