From the Ophthalmology Department, Bambino Gesù IRCCS Children's Hospital, Rome, Italy.
J Cataract Refract Surg. 2022 Jan 1;48(1):56-60. doi: 10.1097/j.jcrs.0000000000000705.
To assess the impact on visual development of multifocal vs monofocal intraocular lenses (IOLs) implantation in children after congenital cataract surgery.
Ophthalmology Department, Bambino Gesù Children's Hospital, Rome, Italy.
Retrospective interventional consecutive case series.
Records of 56 eyes of 43 pediatric patients who underwent congenital cataract surgery with phacoaspiration and simultaneous implantation of the IOL younger than 1 year were reviewed. Corrected distance visual acuity (CDVA), refractive error, and ocular motility disorders were evaluated at follow-up of greater than 4 years.
32 multifocal (18 unilateral, Group A and 14 bilateral, Group B) and 24 monofocal (12 unilateral, Group C and 12 bilateral, Group D) IOLs were implanted. Mean follow-up was 6.67 years. Mean CDVA of the eyes with multifocal IOLs was 0.75 ± 0.46 logMAR in unilateral cataract surgery and 0.34 ± 0.25 logMAR in bilateral ones; with monofocal IOLs was 0.71 ± 0.52 logMAR in unilateral and 0.53 ± 0.43 logMAR in bilateral ones. No statistically significant difference in the CDVA between Groups A and B and Groups C and D were recorded. Final mean spherical equivalent was -3.88 ± 4.73 diopters (D); in Group A, it was -2.74 ± 4.22 D, in Group C was -1.08 ± 1.45 D, in Group B was -4.82 ± 4.64 D, and in Group D was -6.81 ± 4.61 D. The difference was statistically significant between Groups B and D (P = .01), but not between Groups A and C (P = .14). 26 patients (60.4%) showed postoperative strabismus. Surgical correction occurred more in patients with multifocal IOLs implanted (P = .038).
Multifocal IOLs did not show significant advantages in visual development in children after congenital cataract extraction younger than 1 year when compared with monofocal IOLs.
评估在儿童先天性白内障手术后植入多焦点与单焦点人工晶状体（IOL）对视觉发育的影响。
意大利罗马 Bambino Gesù 儿童医院眼科。
回顾性干预连续病例系列。
回顾了 56 只眼 43 名小儿患者的记录，这些患者在 1 岁以下接受了白内障超声乳化吸除术和 IOL 同时植入术。在随访时间超过 4 年时，评估了矫正远视力（CDVA）、屈光不正和眼球运动障碍。
植入了 32 枚多焦点（18 枚单眼，A 组和 14 枚双眼，B 组）和 24 枚单焦点（12 枚单眼，C 组和 12 枚双眼，D 组）IOL。平均随访时间为 6.67 年。多焦点 IOL 眼的平均 CDVA 在单侧白内障手术中为 0.75 ± 0.46 logMAR，在双侧白内障手术中为 0.34 ± 0.25 logMAR；单焦点 IOL 眼的平均 CDVA 在单侧白内障手术中为 0.71 ± 0.52 logMAR，在双侧白内障手术中为 0.53 ± 0.43 logMAR。A 组和 B 组以及 C 组和 D 组之间的 CDVA 无统计学差异。最终平均等效球镜为-3.88 ± 4.73 屈光度（D）；A 组为-2.74 ± 4.22 D，C 组为-1.08 ± 1.45 D，B 组为-4.82 ± 4.64 D，D 组为-6.81 ± 4.61 D。B 组和 D 组之间的差异具有统计学意义（P =.01），但 A 组和 C 组之间的差异无统计学意义（P =.14）。26 名患者（60.4%）出现术后斜视。多焦点 IOL 植入患者更需要手术矫正（P =.038）。
与单焦点 IOL 相比，在 1 岁以下儿童先天性白内障摘除术后，多焦点 IOL 对视觉发育无明显优势。
