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韩国太阴人成年人蔬菜摄入量低、高敏C反应蛋白水平升高与心脏代谢风险之间的关系:一项横断面研究

Relationship between Low Vegetable Consumption, Increased High-Sensitive C-Reactive Protein Level, and Cardiometabolic Risk in Korean Adults with Tae-Eumin: A Cross-Sectional Study.

作者信息

Kim Jieun, Jeong Kyoungsik, Lee Siwoo, Baek Younghwa

机构信息

Future Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

出版信息

Evid Based Complement Alternat Med. 2021 May 11;2021:3631445. doi: 10.1155/2021/3631445. eCollection 2021.

Abstract

An anti-inflammatory diet has many beneficial effects on cardiometabolic diseases. Constitution type of traditional Korean medicine can predict cardiometabolic risk factors. We examined the relationship between vegetable consumption and the high-sensitive C-reactive protein (hs-CRP) level on cardiometabolic risk factors in Korean adults by constitution types. Data from 1,983 eligible participants (mean age, 44.3 years) were included in the present cross-sectional study. The inflammatory status of the participants was categorized into low- (<3.0 mg/L) or high-risk (≥3.0 mg/L) groups based on their constitution types. Cardiometabolic risk factors (abdominal obesity, elevated triglycerides, reduced high-density lipoprotein-cholesterol, elevated blood pressure, elevated fasting plasma glucose, and ≥2 concurrent cardiovascular diseases (CVDs) risk factors) and dietary assessment of the participants were assessed. A total of 11.1% of Tae-eumin (TE) and 4.9% of non-TE groups had a higher hs-CRP level (TE: 6.6 ± 0.2, non-TE: 8.4 ± 0.3) than a low hs-CRP level TE and non-TE (TE: 0.9 ± 0.1, non-TE: 0.6 ± 0.1). Vegetable consumption of <91.5 g/day was highly associated with a high-risk hs-CRP level (adjusted odds ratio (ORs): second tertile (T2): 2.290, (95% confidence interval (CI): 1.285-4.082); first tertile (T1): 2.474 (95% CI: 1.368-4.475), =0.003) compared with that of the highest (T3) in TE. Low (T1 and T2) vegetable consumption was associated with a 54-63% increased prevalence of more than two concurrent CVDs risk factors compared with that of the highest in the TE group (=0.012). Higher vegetable consumption greatly decreased the prevalence of CVDs risk factors by 63-86% in the low-risk and high-risk hs-CRP TE groups. Our results highlight the cardioprotective effects of higher consumption of vegetables in Korean adults with TE. Evidence-based clinical risk factor management and multifaceted approaches at the community and population levels targeting prevention in high-burden groups are recommended to reduce the premature mortality attributed to CVD.

摘要

抗炎饮食对心脏代谢疾病有许多有益影响。中医体质类型可以预测心脏代谢危险因素。我们按体质类型研究了韩国成年人蔬菜摄入量与心脏代谢危险因素高敏C反应蛋白(hs-CRP)水平之间的关系。本横断面研究纳入了1983名符合条件参与者(平均年龄44.3岁)的数据。根据参与者的体质类型,将其炎症状态分为低风险组(<3.0mg/L)或高风险组(≥3.0mg/L)。对参与者的心脏代谢危险因素(腹部肥胖、甘油三酯升高、高密度脂蛋白胆固醇降低、血压升高、空腹血糖升高以及同时存在≥2种心血管疾病(CVD)危险因素)和饮食情况进行评估。太阴人(TE)组中11.1%以及非太阴人组中4.9%的hs-CRP水平高于低hs-CRP水平的太阴人和非太阴人(TE组:6.6±0.2,非TE组:8.4±0.3;TE组:0.9±0.1,非TE组:0.6±0.1)。与太阴人组中最高蔬菜摄入量组(T3)相比,每日蔬菜摄入量<91.5g与高风险hs-CRP水平高度相关(调整后的比值比(ORs):第二三分位数(T2):2.290,(95%置信区间(CI):1.285 - 4.082);第一三分位数(T1):2.474(95%CI:1.368 - 4.475),P = 0.003)。与太阴人组中最高蔬菜摄入量组相比,低(T1和T2)蔬菜摄入量与同时存在超过两种CVD危险因素的患病率增加54 - 63%相关(P = 0.012)。在低风险和高风险hs-CRP太阴人组中,较高的蔬菜摄入量使CVD危险因素的患病率大幅降低63 - 86%。我们的研究结果凸显了在太阴人韩国成年人中较高蔬菜摄入量的心脏保护作用。建议采取基于证据的临床危险因素管理以及在社区和人群层面针对高负担群体预防的多方面方法,以降低归因于CVD的过早死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36ee/8131133/1d977350cf02/ECAM2021-3631445.001.jpg

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