Tian Yue, Liu Linlin, Chen Liang, Zhao Shengdi, Su Ruijun, Zhang Wenzhu, Jiang Aimei, Chen Wenlin, Ge Fei
No. 1 School of Clinical Medicine, Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Mol Clin Oncol. 2021 Jul;15(1):133. doi: 10.3892/mco.2021.2295. Epub 2021 May 11.
Phyllodes tumors (PTs) are rare but complex fibroepithelial lesions of the breast. The present report describes an unusual case of a giant malignant PT with a rich blood supply treated with dominant blood supply internal thoracic artery interventional embolization before surgery. A 41-year-old woman without underlying systemic disease presented with a tumor >20 cm in diameter growing rapidly in the left breast. Radiological results indicated a giant circular tumor with a clear boundary occupying the whole breast, possible invasion of the major pectoralis muscle and several enlarged lymph nodes in the left axillary region. Computed tomography angiography showed a large mass with a rich and powerful blood vessel supply and preoperative interventional embolization was performed to block the internal thoracic artery. Three days after artery embolization, mastectomy and grade I axillary lymph node dissection were performed. The giant tumor measured 17x16x11 cm. The surgery successfully treated the pain and tumor necrosis and the patient received chemotherapy and local radiotherapy. No recurrence was found at the 14-month follow-up.
叶状肿瘤（PTs）是一种罕见但复杂的乳腺纤维上皮性病变。本报告描述了一例不寻常的巨大恶性PT病例，该肿瘤血供丰富，术前采用胸廓内动脉优势血供介入栓塞治疗。一名无基础全身性疾病的41岁女性，左乳出现一个直径>20 cm且生长迅速的肿瘤。影像学结果显示，一个边界清晰的巨大圆形肿瘤占据整个乳房，可能侵犯胸大肌，左腋窝区域有几个肿大淋巴结。计算机断层血管造影显示一个血供丰富且强大的大肿块，并进行了术前介入栓塞以阻断胸廓内动脉。动脉栓塞3天后，进行了乳房切除术和Ⅰ级腋窝淋巴结清扫术。巨大肿瘤尺寸为17×16×11 cm。手术成功缓解了疼痛并使肿瘤坏死，患者接受了化疗和局部放疗。14个月随访未发现复发。
