Zongo Luc, Lange Heiko, Crestini Claudia
Department of Chemical Science and Technologies, University of Rome "Tor Vergata", Via della Ricerca Scientifica, Rome 00133, Italy.
Department of Earth and Environmental Sciences, University of Milano-Bicocca, Piazza della Scienza 1, Milan 20126, Italy.
ACS Omega. 2021 May 11;6(20):13192-13203. doi: 10.1021/acsomega.1c01065. eCollection 2021 May 25.
Microcapsules of sulfited tannin (ST-MCs) were generated for the first time via the sonochemical method. Their stability profile was assessed and set in the general context of tannin microcapsules (TMCs) generated under the same experimental conditions. The analytical data gathered in this work indicate an excellent stability of TMCs over time as well as under high temperature and pressure, which is a major milestone toward the meaningful applications of TMCs in industrial, pharmaceutical, and biomedical applications in which sterilization of TMCs might be a prerequisite. Active release is shown to be efficiently triggered by varying pH and/or salinity, with different profiles for TMCs from sulfited and nonsulfited species. Surfactants also affect the stability of TMCs significantly, with effects eventually amplifiable by pH and the inherent kosmotropic and chaotropic characteristics of salt components in solutions.
首次通过声化学方法制备了亚硫酸化单宁微胶囊（ST-MCs）。在相同实验条件下，评估了它们的稳定性概况，并将其置于单宁微胶囊（TMCs）的总体背景中。这项工作收集的分析数据表明，TMCs在长时间以及高温高压下具有出色的稳定性，这是TMCs在工业、制药和生物医学应用中实现有意义应用的一个重要里程碑，在这些应用中，TMCs的灭菌可能是一个先决条件。结果表明，通过改变pH值和/或盐度可以有效地触发活性释放，亚硫酸化和非亚硫酸化物种的TMCs具有不同的释放曲线。表面活性剂也会显著影响TMCs的稳定性，最终pH值以及溶液中盐成分固有的促离子凝聚和离液序列高的特性会放大这些影响。
