The University of Hong Kong, Pokfulam, Hong Kong, China (P.M.S., A.P.Y., E.C.C., D.S.Y., D.Y.F.).
The Chinese University of Hong Kong, Shatin, Hong Kong, China (S.S.H., J.W.).
Ann Intern Med. 2021 Aug;174(8):1050-1057. doi: 10.7326/M20-7014. Epub 2021 Jun 1.
Central obesity is a major manifestation of metabolic syndrome, which is a common health problem in middle-aged and older adults.
To examine the therapeutic efficacy of tai chi for management of central obesity.
Randomized, controlled, assessor-blinded trial. (ClinicalTrials.gov: NCT03107741).
A single research site in Hong Kong between 27 February 2016 and 28 February 2019.
Adults aged 50 years or older with central obesity.
543 participants were randomly assigned in a 1:1:1 ratio to a control group with no exercise intervention ( = 181), conventional exercise consisting of aerobic exercise and strength training (EX group) ( = 181), and a tai chi group (TC group) ( = 181). Interventions lasted 12 weeks.
Outcomes were assessed at baseline, week 12, and week 38. The primary outcome was waist circumference (WC). Secondary outcomes were body weight; body mass index; high-density lipoprotein cholesterol (HDL-C), triglyceride, and fasting plasma glucose levels; blood pressure; and incidence of remission of central obesity.
The adjusted mean difference in WC from baseline to week 12 in the control group was 0.8 cm (95% CI, -4.1 to 5.7 cm). Both intervention groups showed reductions in WC relative to control (adjusted mean differences: TC group vs. control, -1.8 cm [CI, -2.3 to -1.4 cm]; < 0.001; EX group vs. control: -1.3 cm [CI, -1.8 to -0.9 cm]; < 0.001); both intervention groups also showed reductions in body weight ( < 0.05) and attenuation of the decrease in HDL-C level relative to the control group. The favorable changes in WC and body weight were maintained in both the TC and EX groups, whereas the beneficial effect on HDL-C was only maintained in the TC group at week 38.
High attrition and no dietary intervention.
Tai chi is an effective approach to reduce WC in adults with central obesity aged 50 years or older.
Health and Medical Research Fund.
中心性肥胖是代谢综合征的主要表现之一，也是中老年人群常见的健康问题。
探讨太极拳对中心性肥胖的治疗效果。
随机、对照、评估者设盲试验。（ClinicalTrials.gov：NCT03107741）。
2016 年 2 月 27 日至 2019 年 2 月 28 日期间香港的一个单一研究地点。
年龄在 50 岁及以上、存在中心性肥胖的成年人。
543 名参与者以 1:1:1 的比例随机分为对照组（无运动干预，n=181）、常规运动组（包括有氧运动和力量训练，EX 组，n=181）和太极拳组（TC 组，n=181）。干预持续 12 周。
在基线、第 12 周和第 38 周评估结局。主要结局指标为腰围（WC）。次要结局指标包括体重、体重指数、高密度脂蛋白胆固醇（HDL-C）、甘油三酯和空腹血糖水平、血压以及中心性肥胖缓解的发生率。
对照组从基线到第 12 周的 WC 平均差值为 0.8 cm（95%CI，-4.1 至 5.7 cm）。与对照组相比，两组干预均能降低 WC（调整后的平均差值：TC 组与对照组相比，-1.8 cm[CI，-2.3 至 -1.4 cm]； < 0.001；EX 组与对照组相比：-1.3 cm[CI，-1.8 至 -0.9 cm]； < 0.001）；两组均能降低体重（ < 0.05），且与对照组相比，均能降低 HDL-C 水平。TC 和 EX 两组的 WC 和体重的改善均能持续，而 TC 组仅能在第 38 周维持 HDL-C 的有益作用。
高脱落率和无饮食干预。
太极拳是一种有效的方法，可以降低 50 岁及以上存在中心性肥胖的成年人的 WC。
卫生和医学研究基金。
