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切开复位内固定与非手术治疗闭合性、移位性关节内跟骨骨折的比较:HeFT 随机对照试验的长期随访结果。

Open reduction and internal fixation versus nonoperative treatment for closed, displaced, intra-articular fractures of the calcaneus: long-term follow-up from the HeFT randomized controlled trial.

机构信息

University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

University of Warwick, Coventry, UK.

出版信息

Bone Joint J. 2021 Jun;103-B(6):1040-1046. doi: 10.1302/0301-620X.103B6.BJJ-2020-1962.R2.

DOI:10.1302/0301-620X.103B6.BJJ-2020-1962.R2
PMID:34058883
Abstract

AIMS

We report the long-term outcomes of the UK Heel Fracture Trial (HeFT), a pragmatic, multicentre, two-arm, assessor-blinded, randomized controlled trial.

METHODS

HeFT recruited 151 patients aged over 16 years with closed displaced, intra-articular fractures of the calcaneus. Patients with significant deformity causing fibular impingement, peripheral vascular disease, or other significant limb injuries were excluded. Participants were randomly allocated to open reduction and internal fixation (ORIF) or nonoperative treatment. We report Kerr-Atkins scores, self-reported difficulty walking and fitting shoes, and additional surgical procedures at 36, 48, and 60 months.

RESULTS

Overall, 60-month outcome data were available for 118 patients (78%; 52 ORIF, 66 nonoperative). After 60 months, mean Kerr-Atkins scores were 79.2 (SD 21.5) for ORIF and 76.4 (SD 22.5) for nonoperative. Mixed effects regression analysis gave an estimated effect size of -0.14 points (95% confidence interval -8.87 to 8.59; p = 0.975) in favour of ORIF. There were no between group differences in difficulty walking (p = 0.175), or on the type of shoes worn (p = 0.432) at 60 months. Additional surgical procedures were conducted on ten participants allocated ORIF, compared to four in the nonoperative group (p = 0.043).

CONCLUSION

ORIF of displaced intra-articular calcaneal fractures, not causing fibular impingement, showed no difference in outcomes at 60 months compared to nonoperative treatment, but with an increased risk of additional surgery. Cite this article:  2021;103-B(6):1040-1046.

摘要

目的

我们报告了英国跟骨骨折试验(HeFT)的长期结果,该试验是一项实用的、多中心的、双臂的、评估者盲法的、随机对照试验。

方法

HeFT 招募了 151 名年龄在 16 岁以上的患有闭合性、移位性、关节内跟骨骨折的患者。患有严重畸形导致腓骨撞击、周围血管疾病或其他严重肢体损伤的患者被排除在外。参与者被随机分配接受切开复位内固定(ORIF)或非手术治疗。我们报告了 Kerr-Atkins 评分、自我报告的行走困难和鞋子适配问题,以及在 36、48 和 60 个月时的其他手术程序。

结果

总体而言,118 名患者(78%,52 名 ORIF,66 名非手术治疗)提供了 60 个月的结局数据。60 个月后,ORIF 的平均 Kerr-Atkins 评分为 79.2(SD 21.5),非手术治疗的评分为 76.4(SD 22.5)。混合效应回归分析得出,ORIF 的估计效应大小为-0.14 分(95%置信区间-8.87 至 8.59;p = 0.975)。在 60 个月时,两组在行走困难(p = 0.175)或所穿鞋子类型(p = 0.432)方面没有差异。在接受 ORIF 治疗的 10 名参与者中进行了额外的手术,而非手术组中有 4 名(p = 0.043)。

结论

对于未导致腓骨撞击的移位性关节内跟骨骨折,与非手术治疗相比,ORIF 在 60 个月时的结果没有差异,但手术风险增加。

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