Mishra A, Mishra N, Pati D, Samal D, Kar I B, Mohapatra D, Sarkar D F
Department of Oral & Maxillofacial Surgery, S.C.B. Dental College & Hospital, Cuttack Odisha, India.
Department of Oral & Maxillofacial Surgery, S.C.B. Dental College & Hospital, Cuttack Odisha, India.
Int J Oral Maxillofac Surg. 2022 Feb;51(2):159-165. doi: 10.1016/j.ijom.2021.05.010. Epub 2021 May 28.
The purpose of this study was to evaluate the oncologic safety of submental island flap (SIF) reconstruction in clinically node-negative oral cancer patients. Forty-four clinically node-negative oral cancer patients with tumour size T1-T3 were divided into two groups. The Submental group consisted of 21 patients, who underwent submental island flap reconstruction whereas the control group consisted of 23 patients who underwent reconstruction with other locoregional or free flaps. The locoregional recurrence rate (LRR) and recurrence-free survival (RFS) in these two groups were assessed and compared. The follow-up period in the two groups ranged from six to 28 months, with a median follow-up period of 15 months and 21 months, respectively. Results showed that the LRR in the control and the submental group was 21.7% and 19%, respectively (p = 0.825). Kaplan-Meier curve showed that the difference in recurrence-free survival in the two groups was not statistically significant (p = 0.749). Multivariate and bivariate analyses did not establish any relationship between the predictive parameters and locoregional recurrence. Thus, the Submental island flap is a reliable and versatile locoregional flap for the reconstruction of post-resection defects in oral cancer. It has no predictive influence on locoregional recurrence in clinically node-negative oral cancer patients.
本研究的目的是评估颏下岛状皮瓣（SIF）重建在临床淋巴结阴性口腔癌患者中的肿瘤学安全性。44例肿瘤大小为T1 - T3的临床淋巴结阴性口腔癌患者被分为两组。颏下组由21例患者组成，他们接受了颏下岛状皮瓣重建，而对照组由23例接受其他局部或游离皮瓣重建的患者组成。评估并比较了两组的局部复发率（LRR）和无复发生存率（RFS）。两组的随访期为6至28个月，中位随访期分别为15个月和21个月。结果显示，对照组和颏下组的局部复发率分别为21.7%和19%（p = 0.825）。Kaplan - Meier曲线显示，两组无复发生存率的差异无统计学意义（p = 0.749）。多因素和双因素分析未发现预测参数与局部复发之间存在任何关系。因此，颏下岛状皮瓣是一种可靠且通用的局部皮瓣，用于口腔癌切除术后缺损的重建。它对临床淋巴结阴性口腔癌患者的局部复发没有预测影响。
