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新生儿耐甲氧西林金黄色葡萄球菌(MRSA)颌下脓肿。

Methicillin-resistant (MRSA) submandibular abscess in a neonate.

机构信息

Department of Paediatric Otolaryngology, Addenbrooke's Hospital, Cambridge, UK

Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, UK.

出版信息

BMJ Case Rep. 2021 May 31;14(5):e242258. doi: 10.1136/bcr-2021-242258.

Abstract

Neonatal suppurative submandibular sialadenitis and abscess formation is an exceedingly rare entity. This report describes a complex case of a male neonate with a methicillin-resistant (MRSA) submandibular abscess, requiring emergency intubation due to acute airway compromise. The patient was admitted to the paediatric intensive care unit, received appropriate antibiotic treatment and underwent urgent surgical drainage of the abscess. He made a full recovery and remains well 18 months later. No comorbidities or common risk factors for the disease were identified. Although extremely uncommon, neonatal submandibular abscesses can lead to significant morbidity. Neonates tend to present insidiously, and sudden clinical deterioration with airway compromise is possible. MRSA has been increasingly implicated in these infections, even in the absence of relevant risk factors. As such, continued clinical vigilance is essential for prompt diagnosis and prevention of life-threatening complications. Multidisciplinary input is paramount for appropriate management of these complex infections.

摘要

新生儿化脓性颌下唾液腺炎和脓肿形成是一种极其罕见的疾病。本报告描述了一例复杂的男性新生儿耐甲氧西林金黄色葡萄球菌(MRSA)颌下脓肿病例,由于急性气道阻塞需要紧急气管插管。该患儿入住儿科重症监护病房,接受了适当的抗生素治疗,并进行了脓肿的紧急外科引流。他完全康复,18 个月后情况良好。未发现该疾病的任何合并症或常见危险因素。尽管非常罕见,但新生儿颌下脓肿可导致严重的发病率。新生儿往往隐匿性发病,并且气道阻塞可能导致病情突然恶化。即使没有相关的危险因素,MRSA 也越来越多地与这些感染有关。因此,持续的临床警惕对于及时诊断和预防危及生命的并发症至关重要。多学科的投入对于这些复杂感染的适当管理至关重要。

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