Pediatric Surgery Department, Military Central Hospital, Algiers, Algeria.
J Endourol. 2021 Dec;35(12):1808-1812. doi: 10.1089/end.2020.1217.
The main objective of our prospective, descriptive, monocentric, longitudinal study is to demonstrate the feasibility of vesicoscopic cross-trigonal ureteral reimplantation under CO pneumovesicum in treatment on primary vesicoureteral reflux (VUR), analyze results, and specify the age limit of this approach. A total of 60 patients underwent transvesicoscopic ureteral reimplantation (33 boys, 27 girls) by the same surgeon from May 2011 to May 2015. All patients had primary VUR, and surgery was performed because of breakthrough urinary tract infection despite antibiotic prophylaxis and persistent high grade of VUR, especially in association with significant renal scarring, mean age at operation was 47.47 months (6 month-12 years). Of the 60 patients, 34 had bilateral reflux and 26 had unilateral reflux. The reflux grade in the total of 94 ureters was grade IV, V in 59.57%, grade III in 35.11%, and grade II in 5.32% in association with contralateral high-grade VUR. The transvesicoscopic procedure was effectively completed in all patients without perioperative complication except one case of pneumoperitoneum that required exsufflation by open laparoscopy. The mean overall operative time decreased significantly with an average of 58.43 ± 11.26 minutes for unilateral reimplantation and 101.18 ± 26.5 minutes for bilateral reimplantation. The postoperative hospital stay was 3 days for all patients. The mean follow-up period was 3 years. Cystography was performed 3 months after surgery in all patients and showed the disappearance of VUR in 57/60 patients (95%) or 91/94 of ureters (97%). Persistent VUR was documented in 3 of 94 ureters and had resolved spontaneously at 12 months after reimplantation. Our preliminary results indicate that vesicoscopic ureteral reimplantation is safe and effective procedure with minimal morbidity when compared to traditional open method. It can be applied in children younger than 12 months.
我们的前瞻性、描述性、单中心、纵向研究的主要目的是证明在 CO 气膀胱下经膀胱镜行交叉三角状输尿管再植术治疗原发性膀胱输尿管反流(VUR)的可行性,分析结果,并确定该方法的年龄限制。2011 年 5 月至 2015 年 5 月,同一位外科医生为 60 例患者(33 名男孩,27 名女孩)进行了经膀胱镜输尿管再植术。所有患者均为原发性 VUR,由于尽管使用了抗生素预防,但仍出现尿路感染突破,或持续性高级别 VUR,特别是与显著的肾瘢痕相关,手术时的平均年龄为 47.47 个月(6 个月-12 岁)。60 例患者中,34 例为双侧反流,26 例为单侧反流。94 条输尿管的反流程度中,IV 级、V 级占 59.57%,III 级占 35.11%,II 级占 5.32%,同时伴有对侧高级别 VUR。所有患者均成功完成经膀胱镜手术,无围手术期并发症,仅 1 例出现气腹,需行开放式腹腔镜放气。单侧再植的平均总手术时间显著缩短,平均为 58.43±11.26 分钟,双侧再植为 101.18±26.5 分钟。所有患者术后住院时间均为 3 天。平均随访时间为 3 年。所有患者术后 3 个月均行膀胱造影检查,57/60 例(95%)或 91/94 例(97%)患者的 VUR 消失。94 条输尿管中有 3 条仍存在 VUR,但在再植后 12 个月内自行缓解。我们的初步结果表明,与传统的开放方法相比,经膀胱镜输尿管再植术是一种安全有效的方法,发病率较低。它可以应用于 12 个月以下的儿童。