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显微镜下结肠炎与结肠腺瘤风险:一项多中心回顾性队列研究

Microscopic Colitis and Risk of Colon Adenomas: A Multicenter Retrospective Cohort Study.

作者信息

Kamboj Amrit K, Zylberberg Haley M, Lane Conor M, Voth Elida, Tome June, Cuir Nicole D, Lennon Ryan J, Khanna Sahil, Lebwohl Benjamin, Pardi Darrell S

机构信息

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

Columbia University Medical Center, New York, New York.

出版信息

Clin Gastroenterol Hepatol. 2022 Apr;20(4):e902-e904. doi: 10.1016/j.cgh.2021.05.050. Epub 2021 May 29.

DOI:10.1016/j.cgh.2021.05.050
PMID:34062313
Abstract

Microscopic colitis (MC) is a common cause of chronic watery diarrhea, with the highest incidence in women over age 50. Cross-sectional studies have suggested that patients with MC have a lower incidence of adenomatous colon polyps compared with those without MC. The existing literature is limited by cross-sectional design, small sample sizes, lack of longitudinal follow-up, and the use of average-risk patients, rather than those with chronic diarrhea, as controls. We aimed to explore the association between MC and colon adenomas.

摘要

显微镜下结肠炎(MC)是慢性水样腹泻的常见病因,在50岁以上女性中发病率最高。横断面研究表明,与无MC的患者相比,MC患者的结肠腺瘤性息肉发病率较低。现有文献受横断面设计、样本量小、缺乏纵向随访以及使用平均风险患者而非慢性腹泻患者作为对照的限制。我们旨在探讨MC与结肠腺瘤之间的关联。

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引用本文的文献

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Update on the Epidemiology and Management of Microscopic Colitis.显微镜下结肠炎的流行病学与管理最新进展
Clin Gastroenterol Hepatol. 2025 Feb;23(3):490-500. doi: 10.1016/j.cgh.2024.08.026. Epub 2024 Sep 11.
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Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care.老年医学中小肠结肠炎的诊断和药物治疗管理。
Drugs Aging. 2024 Feb;41(2):113-123. doi: 10.1007/s40266-023-01094-6. Epub 2024 Jan 17.
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Editorial: The Dark Side of Microscopic Colitis.社论:显微镜下结肠炎的阴暗面
Front Med (Lausanne). 2021 Dec 2;8:809136. doi: 10.3389/fmed.2021.809136. eCollection 2021.
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Clinical Characteristics and Treatment Response in Microscopic Colitis Based on Age at Diagnosis: A Multicenter Retrospective Study.基于诊断时年龄的显微镜结肠炎的临床特征和治疗反应:一项多中心回顾性研究。
Dig Dis Sci. 2022 Jul;67(7):3108-3114. doi: 10.1007/s10620-021-07162-4. Epub 2021 Jul 20.