Kamboj Amrit K, Zylberberg Haley M, Lane Conor M, Voth Elida, Tome June, Cuir Nicole D, Lennon Ryan J, Khanna Sahil, Lebwohl Benjamin, Pardi Darrell S
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Columbia University Medical Center, New York, New York.
Clin Gastroenterol Hepatol. 2022 Apr;20(4):e902-e904. doi: 10.1016/j.cgh.2021.05.050. Epub 2021 May 29.
Microscopic colitis (MC) is a common cause of chronic watery diarrhea, with the highest incidence in women over age 50. Cross-sectional studies have suggested that patients with MC have a lower incidence of adenomatous colon polyps compared with those without MC. The existing literature is limited by cross-sectional design, small sample sizes, lack of longitudinal follow-up, and the use of average-risk patients, rather than those with chronic diarrhea, as controls. We aimed to explore the association between MC and colon adenomas.
显微镜下结肠炎(MC)是慢性水样腹泻的常见病因,在50岁以上女性中发病率最高。横断面研究表明,与无MC的患者相比,MC患者的结肠腺瘤性息肉发病率较低。现有文献受横断面设计、样本量小、缺乏纵向随访以及使用平均风险患者而非慢性腹泻患者作为对照的限制。我们旨在探讨MC与结肠腺瘤之间的关联。