Al-Amri Ayman, Al-Khabori Murtadha, Al-Riyami Nihal, Al-Haddabi Ibrahim
Surgery Department, Sultan Qaboos University Hospital, Muscat, Oman.
Haematology Department, Sultan Qaboos University Hospital, Muscat, Oman.
Int J Surg Case Rep. 2021 Jun;83:106021. doi: 10.1016/j.ijscr.2021.106021. Epub 2021 May 26.
Histiocytic sarcoma (HS) is a rare, aggressive malignant neoplasm of hematopoietic cell origin. Primary HS of the proximal humerus, without involvement of lymph nodes or bone marrow, or systemic features, is very rare.
We report a rare case of primary bony HS of the proximal humerus without bone marrow involvement in a healthy 33-year-old pregnant woman. She was successfully treated with surgical resection during pregnancy and radiotherapy post-delivery.
This is the first report of a patient with primary bony HS during pregnancy. This highlights the fact that although HS is a neoplasm of hemolymphoid cell lineage, it frequently arises in non-lymphoid organs.
This case emphasizes the importance of a multidisciplinary approach and the need for balancing treatment risk in a patient with primary bone HS during pregnancy.
组织细胞肉瘤（HS）是一种罕见的、侵袭性的造血细胞源性恶性肿瘤。肱骨近端的原发性HS，无淋巴结或骨髓受累，亦无全身症状，极为罕见。
我们报告一例罕见的肱骨近端原发性骨HS病例，患者为一名33岁的健康孕妇，无骨髓受累。她在孕期接受了手术切除，并在产后接受了放疗，治疗成功。
这是首例关于孕期原发性骨HS患者的报告。这凸显了一个事实，即尽管HS是一种血液淋巴细胞谱系的肿瘤，但它经常发生于非淋巴器官。
本病例强调了多学科方法的重要性，以及在孕期原发性骨HS患者中平衡治疗风险的必要性。
