剪切波弹性成像在异体造血干细胞移植成年患者肝窦阻塞综合征检测中的应用
Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation.
作者信息
Schulz Marten, Vuong Lam Giang, Müller Hans Peter, Maibier Martin, Tacke Frank, Blau Igor Wolfgang, Wree Alexander
机构信息
Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum (CVK) und Campus Charité Mitte (CCM), 13353 Berlin, Germany.
Department of Hematology, Oncology and Tumor Immunology, Charité-Universitätsmedizin Campus Virchow-Klinikum (CVK), 13353 Berlin, Germany.
出版信息
Diagnostics (Basel). 2021 May 21;11(6):928. doi: 10.3390/diagnostics11060928.
Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients developed SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT.
肝窦阻塞综合征（SOS），也称为静脉闭塞性疾病（VOD），可能是造血干细胞移植（HSCT）后一种危及生命的并发症。诊断通常很困难，传统上基于临床参数。剪切波弹性成像（SWE）是一种使用超声的现代非侵入性肝脏硬度测量技术。在这项单中心研究中，我们评估了SWE在2020年2月至2020年8月在现实环境中接受HSCT的63例成年患者中诊断SOS/VOD的作用。三名患者发生了SOS/VOD。这三名患者的剪切波速度均有所增加，表明该方法可能有助于HSCT后SOS/VOD的诊断确立。
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