Chen Yi-Ping, Tasi Xian-Wen, Chang Ko, Cao Xuan-Di, Chen Jung-Ren, Liao Chien-Sen
Department of Medical Laboratory, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung 81267, Taiwan.
Department of Nursing and Medical Quality Management Center, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung 81267, Taiwan.
Antibiotics (Basel). 2021 May 20;10(5):608. doi: 10.3390/antibiotics10050608.
This study aimed to investigate the effects of multi-drug-resistant organism (MDRO) infection and other factors on the length of hospital stay (LOS) of patients in the respiratory care ward (RCW) of a regional hospital in Taiwan. In this retrospective study, we collected cases from MDRO-infected patients in the RCW from January 2016 to March 2020. The RCW comprises 13 beds in total. There were 106 infected patients, of which 42 were in the case group (infected with MDROs) and 64 were in the control group (not infected with MDROs). Clinical specimens were inoculated in a selective medium to isolate the pathogenic bacteria by standard procedures. The results showed the main factors affecting the LOS were: patients with MDRO infection, patients discharged from the RCW, and patients who underwent catheterization. The LOS of patients infected with MDROs was significantly longer than that of patients without MDRO infection (β = 0.55, 95% CI = 0.02-1.09), with the case group and the control group being 479.8 ± 546.5 and 307.3 ± 436.2 days, respectively. Infection with carbapenem-resistant (CRPA) was associated with a longer LOS than other MDRO strains. These findings have important implications for infection control in RCW and in better tracking the health of patients.
本研究旨在调查多重耐药菌（MDRO）感染及其他因素对台湾某地区医院呼吸照护病房（RCW）患者住院时间（LOS）的影响。在这项回顾性研究中，我们收集了2016年1月至2020年3月RCW中MDRO感染患者的病例。RCW共有13张床位。共有106例感染患者，其中42例在病例组（感染MDROs），64例在对照组（未感染MDROs）。临床标本接种于选择性培养基中，通过标准程序分离病原菌。结果显示影响住院时间的主要因素为：MDRO感染患者、从RCW出院的患者以及接受导管插入术的患者。感染MDROs的患者住院时间显著长于未感染MDRO的患者（β = 0.55，95%CI = 0.02 - 1.09），病例组和对照组分别为479.8±546.5天和307.3±436.2天。耐碳青霉烯类（CRPA）感染比其他MDRO菌株与更长的住院时间相关。这些发现对RCW的感染控制以及更好地追踪患者健康具有重要意义。
