组蛋白基因第三密码子位置 GC 含量进化的腺嘌呤/胸腺嘧啶有害选择模型。
The Adenine/Thymine Deleterious Selection Model for GC Content Evolution at the Third Codon Position of the Histone Genes in .
机构信息
Division of Science and Technology, Tokushima University, 2-1 Minamijosanjima-cho, Tokushima 770-8506, Japan.
出版信息
Genes (Basel). 2021 May 12;12(5):721. doi: 10.3390/genes12050721.
Abstract
The evolution of the GC (guanine cytosine) content at the third codon position of the histone genes (, , , , , , , , and ) in 12 or more species is reviewed. For explaining the evolution of the GC content at the third codon position of the genes, a model assuming selection with a deleterious effect for adenine/thymine and a size effect is presented. The applicability of the model to whole-genome genes is also discussed.
摘要
本文回顾了 12 种或更多物种组蛋白基因（ 、 、 、 、 、 、 和 ）第三密码子位置 GC（鸟嘌呤胞嘧啶）含量的进化。为了解释基因第三密码子位置 GC 含量的进化，提出了一个假设选择具有有害腺嘌呤/胸腺嘧啶效应和大小效应的模型。还讨论了该模型对全基因组基因的适用性。
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