Aarnio P
Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Finland.
Scand J Thorac Cardiovasc Surg. 1988;22(2):105-10. doi: 10.3109/14017438809105938.
Both right and left internal mammary artery (IMA) were dissected free in six dogs via median sternotomy, the left together with 2 cm-wide surrounding tissue and the right as naked artery. Free IMA grafts (3 cm long) were anastomosed end-to-end to the femoral arteries as bypass. Graft patency was assessed by palpation and Doppler analysis twice monthly. At 6 months all grafts were patent. They were harvested for light and scanning electron microscopy (SEM). Intimal thickening was seen in one specimen from each side. Medial fibrosis was more common in the IMA grafts with surrounding tissue. SEM showed endothelium in all grafts, but with some degeneration of endothelial cells. The study thus demonstrated maintenance of patency in free IMA grafts, which did not differ if the graft had been taken with or without surrounding tissue.
通过正中胸骨切开术在6只犬中游离出左右两侧的胸廓内动脉（IMA），左侧连同其周围2厘米宽的组织，右侧则作为裸动脉。游离的IMA移植物（3厘米长）端端吻合至股动脉作为旁路。每月通过触诊和多普勒分析评估移植物通畅情况两次。6个月时所有移植物均通畅。将它们取下用于光镜和扫描电子显微镜（SEM）检查。两侧各有一个标本出现内膜增厚。内侧纤维化在带有周围组织的IMA移植物中更为常见。SEM显示所有移植物均有内皮，但内皮细胞有一些退变。该研究因此证明了游离IMA移植物通畅性得以维持，无论移植物是否带有周围组织，其通畅情况并无差异。
