Corniola Marco Vincenzo, König Marton, Meling Torstein Ragnar
Department of Neurosurgery, Geneva University Hospitals, 1205 Geneva, Switzerland.
Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
Cancers (Basel). 2021 May 17;13(10):2420. doi: 10.3390/cancers13102420.
Cavernous sinus meningiomas (CSM) are mostly non-surgical tumors. Stereotactic radiosurgery (SRS) or radiotherapy (SRT) allow tumor control and improvement of pre-existing cranial nerve (CN) deficits. We report the case of a patient with radiation-induced internal carotid artery (ICA) stenosis. We complete the picture with a review of the literature of vascular and non-vascular complications following the treatment of CSMs with SRS or SRT.
After a case description, a systematic literature review is presented, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2015 guidelines.
115 abstracts were screened and 70 titles were retained for full-paper screening. A total of 58 articles did not meet the inclusion criteria. There were 12 articles included in our review, with a follow-up ranging from 33 to 120 months. Two cases of post-SRT ischemic stroke and one case of asymptomatic ICA stenosis were described. Non-vascular complications were reported in all articles.
SRS and SRT carry fewer complications than open surgery, with similar rates of tumor control. Our case shows the importance of a follow-up of irradiated CSMs not only by a radio-oncologist, but also by a neurosurgeon, illustrating the importance of multidisciplinary management of CSMs.
海绵窦脑膜瘤(CSM)大多为不可手术切除的肿瘤。立体定向放射外科治疗(SRS)或放射治疗(SRT)可实现肿瘤控制并改善已存在的颅神经(CN)功能缺损。我们报告一例放射诱发颈内动脉(ICA)狭窄的患者。我们通过回顾SRS或SRT治疗CSM后血管及非血管并发症的文献完善了这一情况。
在病例描述之后,根据2015年系统评价与Meta分析优先报告条目指南进行系统的文献回顾。
筛选了115篇摘要,保留70篇标题进行全文筛选。共有58篇文章不符合纳入标准。我们的综述纳入12篇文章,随访时间为33至120个月。描述了2例SRT后缺血性卒中及1例无症状ICA狭窄。所有文章均报告了非血管并发症。
SRS和SRT比开放手术并发症更少,肿瘤控制率相似。我们的病例显示,不仅放疗科医生,神经外科医生对接受放疗的CSM进行随访也很重要,这说明了CSM多学科管理的重要性。