Wójcik Natalia Anna, Ali Sharafat, Karczewski Jakub Lech, Jonson Bo, Bartmański Michał, Barczyński Ryszard Jan
Advanced Materials Center, Gdańsk University of Technology, ul. Narutowicza 11/12, 80-233 Gdańsk, Poland.
Institute of Nanotechnology and Materials Engeenering, Faculty of Applied Physics and Mathematics, Gdańsk University of Technology, Narutowicza Street 11/12, 80-233 Gdańsk, Poland.
Materials (Basel). 2021 May 17;14(10):2626. doi: 10.3390/ma14102626.
Bioactive glasses have recently been extensively used to replace, regenerate, and repair hard tissues in the human body because of their ability to bond with living tissue. In this work, the effects of replacing NaO with MgO on the electrical, biosolubility, and thermal properties of the target glass 10NaO-60PO-30CaO (in mol%) were investigated. The electrical properties of the glasses were studied with the impedance spectroscopy technique. At 473 K, DC conductivity values decreased from 4.21 × 10 to 4.21 × 10 S cm after complete substitution of MgO for NaO. All samples had a similar activation energy of the DC conduction process ~1.27 eV. Conduction mechanisms were found to be due to hop of ions: Na, Mg and probable H. FTIR analysis showed that, as the Mg content increased, the Q unit (PO) shifted towards higher wavenumbers. The proportion of Q unit (PO) decreased in the glass structure. This confirmed that the replacement of Na by Mg was accompanied by concurrent polymerization of the calcium-phosphate glass network. The biosolubility test in the phosphate-buffered saline solution showed that the magnesium addition enhanced the biosolubility properties of NaO-CaO-PO glasses by increasing their dissolution rate and supporting forming CaP-rich layers on the surface. The glass transition temperature increased, and thermal stability decreased substantially upon substitution of NaO by MgO.
由于具有与活组织结合的能力，生物活性玻璃最近被广泛用于替代、再生和修复人体硬组织。在这项工作中，研究了用MgO替代NaO对目标玻璃10NaO-60PO-30CaO（摩尔百分比）的电学、生物溶解性和热性能的影响。采用阻抗谱技术研究了玻璃的电学性能。在473K时，用MgO完全替代NaO后，直流电导率值从4.21×10降至4.21×10 S/cm。所有样品的直流传导过程具有相似的活化能~1.27eV。发现传导机制是由于离子（Na、Mg和可能的H）的跳跃。傅里叶变换红外光谱（FTIR）分析表明，随着Mg含量的增加，Q单元（PO）向更高波数移动。玻璃结构中Q单元（PO）的比例降低。这证实了用Mg替代Na伴随着磷酸钙玻璃网络的同时聚合。在磷酸盐缓冲盐溶液中的生物溶解性测试表明，添加镁通过提高其溶解速率并支持在表面形成富含CaP的层，增强了NaO-CaO-PO玻璃的生物溶解性。用MgO替代NaO后，玻璃化转变温度升高，热稳定性大幅下降。
