Mak J W, Yong H S, Lim P K, Tan M A
Institute for Medical Research, Kuala Lumpur, Malaysia.
Southeast Asian J Trop Med Public Health. 1988 Mar;19(1):7-9.
Biotechnological tools are being used in malaria, filariasis and dengue research. The main emphasis has been on the production of reagents for immunodiagnosis and research. In this respect monoclonal antibodies (McAbs) against various species and stages of the above pathogens have been produced. It is hoped that these McAbs will be useful not only in immunodiagnosis but also for seroepidemiological applications. A DNA probe against Brugia malayi has been tested in Malaysia and was found to be sensitive and specific.
生物技术工具正应用于疟疾、丝虫病和登革热研究。主要重点在于生产用于免疫诊断和研究的试剂。在这方面，已经制备了针对上述病原体不同种类和阶段的单克隆抗体（McAbs）。人们希望这些单克隆抗体不仅在免疫诊断中有用，而且在血清流行病学应用中也有用。一种针对马来布鲁线虫的DNA探针已在马来西亚进行测试，结果发现其具有敏感性和特异性。
