Vest D K
Department of Zoology, Washington State University, Pullman 99164-4220.
Toxicon. 1988;26(4):417-9. doi: 10.1016/0041-0101(88)90012-8.
The Texas night snake (Hypsiglena torquata texana), a small opisthoglyphic colubrid snake, produces a Duvernoy's secretion which has a relatively low lethal toxicity for mice, but produces pain, hemorrhage, and oedema at the site of injection. The subcutaneous LD50 of Hypsiglena torquata texana Duvernoy's secretion in Swiss-Webster mice was 26 mg/kg. Local hemorrhaging occurred at doses as low as 2.0 micrograms/mouse, while marked hemorrhage and oedema resulted at doses greater than 200 micrograms/mouse. The dry secretion contained 77% protein, and SDS-PAGE electrophoresis revealed the presence of seven major proteinaceous components.
德州夜蛇（Hypsiglena torquata texana）是一种小型后毒牙游蛇科蛇类，能产生对小鼠致死毒性相对较低的杜氏腺分泌物，但在注射部位会引起疼痛、出血和水肿。德州夜蛇杜氏腺分泌物在瑞士韦伯斯特小鼠中的皮下半数致死剂量为26毫克/千克。低至2.0微克/小鼠的剂量就会出现局部出血，而剂量大于200微克/小鼠则会导致明显的出血和水肿。干燥分泌物含77%的蛋白质，十二烷基硫酸钠-聚丙烯酰胺凝胶电泳显示存在七种主要蛋白质成分。
