Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.
Infraredx, Inc., Bedford, MA 01730, USA.
Sensors (Basel). 2021 May 19;21(10):3540. doi: 10.3390/s21103540.
As a well-known medical imaging methodology, intravascular ultrasound (IVUS) imaging plays a critical role in diagnosis, treatment guidance and post-treatment assessment of coronary artery diseases. By cannulating a miniature ultrasound transducer mounted catheter into an artery, the vessel lumen opening, vessel wall morphology and other associated blood and vessel properties can be precisely assessed in IVUS imaging. Ultrasound transducer, as the key component of an IVUS system, is critical in determining the IVUS imaging performance. In recent years, a wide range of achievements in ultrasound transducers have been reported for IVUS imaging applications. Herein, a comprehensive review is given on recent advances in ultrasound transducers for IVUS imaging. Firstly, a fundamental understanding of IVUS imaging principle, evaluation parameters and IVUS catheter are summarized. Secondly, three different types of ultrasound transducers (piezoelectric ultrasound transducer, piezoelectric micromachined ultrasound transducer and capacitive micromachined ultrasound transducer) for IVUS imaging are presented. Particularly, the recent advances in piezoelectric ultrasound transducer for IVUS imaging are extensively examined according to their different working mechanisms, configurations and materials adopted. Thirdly, IVUS-based multimodality intravascular imaging of atherosclerotic plaque is discussed. Finally, summary and perspectives on the future studies are highlighted for IVUS imaging applications.
作为一种著名的医学成像方法,血管内超声(IVUS)成像在冠状动脉疾病的诊断、治疗指导和治疗后评估中起着至关重要的作用。通过将微型超声换能器安装在导管中插入动脉,可以精确评估 IVUS 成像中的血管腔开口、血管壁形态以及其他相关的血液和血管特性。超声换能器作为 IVUS 系统的关键组成部分,对 IVUS 成像性能至关重要。近年来,已有大量关于用于 IVUS 成像应用的超声换能器的研究成果被报道。本文对用于 IVUS 成像的超声换能器的最新进展进行了全面综述。首先,总结了 IVUS 成像原理、评价参数和 IVUS 导管的基本认识。其次,介绍了用于 IVUS 成像的三种不同类型的超声换能器(压电超声换能器、压电微机械超声换能器和电容式微机械超声换能器)。特别地,根据不同的工作机制、结构和采用的材料,对用于 IVUS 成像的压电超声换能器的最新进展进行了广泛的考察。第三,讨论了基于 IVUS 的动脉粥样硬化斑块的多模态血管内成像。最后,对 IVUS 成像应用的未来研究进行了总结和展望。