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电损伤与烧伤的治疗:病理生理学综述及患者管理方案比较

The treatment of electrical injury compared to burn injury: a review of pathophysiology and comparison of patient management protocols.

作者信息

Rouse R G, Dimick A R

出版信息

J Trauma. 1978 Jan;18(1):43-7. doi: 10.1097/00005373-197801000-00008.

DOI:10.1097/00005373-197801000-00008
PMID:340708
Abstract

Because of basic differences in pathophysiology, patients with electrical injury require therapeutic measures quite separate and distinct from patients with flame burns. Fluid requirements are much greater for the electrical-injured patient due to the depth of the injury and frequent occurrence of pigment in the urine. Fasciotomy with surgical exploration for determination of tissue viability is usually required in areas of obvious or questionable viability in patients with electrical injury. Sulfamylon is preferred for topical antibacterial therapy in electrical injury, because of its excellent penetration into deeper tissues. With this regimen of conservative surgical debridement of necrotic tissue, in many patients we have been able to salvage limbs and, in particular, preserve function.

摘要

由于病理生理学的基本差异,电烧伤患者所需的治疗措施与火焰烧伤患者截然不同。电烧伤患者的液体需求量大得多,这是因为损伤深度深且尿液中常有色素。对于电烧伤患者,在明显或可疑存活能力的区域通常需要进行筋膜切开术并进行手术探查以确定组织的存活能力。磺胺米隆因其能很好地渗透到深层组织中而成为电烧伤局部抗菌治疗的首选药物。采用这种保守手术清除坏死组织的方案,我们在许多患者中成功保住了肢体,尤其是保留了功能。

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The treatment of electrical injury compared to burn injury: a review of pathophysiology and comparison of patient management protocols.电损伤与烧伤的治疗:病理生理学综述及患者管理方案比较
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引用本文的文献

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The occurrence of single and multiple organ dysfunction in pediatric electrical versus other thermal burns.小儿电击伤与其他热烧伤中单器官和多器官功能障碍的发生情况
J Trauma Acute Care Surg. 2017 May;82(5):946-951. doi: 10.1097/TA.0000000000001356.
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[Early surgical management of severe burns].[严重烧伤的早期手术治疗]
Unfallchirurg. 2006 Apr;109(4):270-7. doi: 10.1007/s00113-006-1073-x.
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Electric field-induced functional reductions in the K+ channels mainly resulted from supramembrane potential-mediated electroconformational changes.
电场诱导的钾离子通道功能降低主要源于超膜电位介导的电构象变化。
Biophys J. 1998 Jul;75(1):196-206. doi: 10.1016/S0006-3495(98)77506-X.