Townsend Robert K, Fargen Kyle M
Department of Neurosurgery, Wake Forest University, Winston-Salem, NC 27101, USA.
Life (Basel). 2021 May 31;11(6):508. doi: 10.3390/life11060508.
Idiopathic intracranial hypertension (IIH) is a debilitating condition that has traditionally been difficult to treat. In recent years, there has been increasing focus on the role of intracranial venous hypertension in the pathophysiology of IIH. Based on increased understanding of this pathophysiology, venous sinus stenting (VSS) has emerged as a safe and reliable treatment for a certain population of patients with IIH. Stratifying patients with IIH based on the status of their venous outflow can provide insight into which patients may enjoy reduction in their symptoms after VSS and provides information regarding why some patients may have symptom recurrence. The traditional view of IIH as a disease due to obesity in young women has been cast into doubt as the understanding of the role of intracranial venous hypertension has improved.
特发性颅内高压(IIH)是一种使人衰弱的病症,传统上难以治疗。近年来,人们越来越关注颅内静脉高压在IIH病理生理学中的作用。基于对这种病理生理学的深入理解,静脉窦支架置入术(VSS)已成为治疗特定人群IIH患者的一种安全可靠的方法。根据IIH患者的静脉流出状态进行分层,可以深入了解哪些患者在接受VSS治疗后症状可能减轻,并提供有关为什么有些患者可能出现症状复发的信息。随着对颅内静脉高压作用的认识不断提高,IIH作为年轻女性肥胖所致疾病的传统观点受到了质疑。