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[暴发性原发性肺炎球菌性腹膜炎]

[Primary pneumococcal peritonitis with a fulminant course].

作者信息

Tolmáči Benjamín, Klein Jiří, Žuffa Peter, Řehulková Alona

出版信息

Vnitr Lek. 2021 Spring;67(E-2):34-37.

Abstract

INTRODUCTION

Primary peritonitis is an inflammation of the peritoneal cavity in the absence of a localized intra-abdominal source. It is included in the differential diagnosis of acute abdomen and can be potentially life-threatening. Pneumococci were a frequent pathogen causing primary peritonitis especially in the preantibiotic era. Nowadays, they act as an uncommon primary pathogen. Pneumococcal peritonitis in adults is more frequently seen in cases of liver cirrhosis with ascites and other pre-existing conditions. Primary pneumococcal peritonitis is uncommon in healthy individuals and therefore its diagnosis is difficult. Secondary peritonitis has to be excluded.

CASE REPORT

A 36-year-old woman was admitted to our surgery department with symptoms of severe sepsis. She reported a sudden onset of diffuse abdominal pain and was eight weeks after delivery per vias naturales. A computed tomography scan of the abdomen with intravenous contrast has not demonstrated any pathology explaining the condition of our patient. Empiric anti-microbial therapy with broad-spectrum antibiotics was commenced and a laparotomy was performed, which also did not reveal any source of infection. Purulent odorless fluid was found in the peritoneal cavity. Peritoneal lavage with an antiseptic was performed. Cultures from peritoneal fluid demonstrated a monobacterial growth of Streptococcus pneumoniae. The condition of our patient improved after continued adequate antibiotic therapy and lavage.

CONCLUSION

Primary pneumococcal peritonitis is difficult to diagnose in healthy individuals, since it is mimicking secondary peritonitis that has to be excluded. A clinical diagnose without surgical intervention is impossible in most cases. Surgical treatment has an important role in both the diagnosis and management of primary pneumococcal peritonitis, same as adequate antibiotic therapy. Primary peritonitis should be a part of the differential diagnosis of patients presenting with acute abdominal pain.

摘要

引言

原发性腹膜炎是指在无局限性腹腔内感染源的情况下腹膜腔的炎症。它包含在急腹症的鉴别诊断中,且可能危及生命。肺炎球菌是引起原发性腹膜炎的常见病原体,尤其是在抗生素时代之前。如今,它们作为原发性病原体已较为罕见。成人肺炎球菌性腹膜炎在肝硬化腹水及其他既有病症的病例中更为常见。原发性肺炎球菌性腹膜炎在健康个体中并不常见,因此其诊断较为困难。必须排除继发性腹膜炎。

病例报告

一名36岁女性因严重脓毒症症状入住我院外科。她自述突发弥漫性腹痛,且自然分娩后已八周。腹部增强CT扫描未发现任何可解释患者病情的病变。开始使用广谱抗生素进行经验性抗菌治疗,并实施了剖腹探查术,但也未发现任何感染源。在腹膜腔中发现了无异味的脓性液体。进行了用消毒剂的腹膜灌洗。腹膜液培养显示肺炎链球菌单菌生长。在持续进行充分的抗生素治疗和灌洗后,患者病情好转。

结论

原发性肺炎球菌性腹膜炎在健康个体中难以诊断,因为它类似继发性腹膜炎,必须予以排除。在大多数情况下,不进行手术干预就无法进行临床诊断。手术治疗在原发性肺炎球菌性腹膜炎的诊断和治疗中都具有重要作用,充分的抗生素治疗亦是如此。原发性腹膜炎应作为急性腹痛患者鉴别诊断的一部分。

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