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平等获得肾移植机会:欧洲视角。

Equity of access to renal transplantation: a European perspective.

机构信息

Edinburgh Transplant Centre, Royal Infirmary of Edinburgh.

Department of Clinical Surgery, University of Edinburgh, Edinburgh, UK.

出版信息

Curr Opin Organ Transplant. 2021 Aug 1;26(4):347-352. doi: 10.1097/MOT.0000000000000895.

DOI:10.1097/MOT.0000000000000895
PMID:34074941
Abstract

PURPOSE OF REVIEW

Renal transplantation offers the chance for patients with end-stage renal disease (ESRD) to have a significantly longer, healthier and better quality life compared with remaining on dialysis. Inequities have been demonstrated at multiple points in the transplantation pathway. In this review, the factors contributing to inequity in access to renal transplantation will be explored from a European perspective.

RECENT FINDINGS

Despite improvements in patient assessment and revision of organ-offering schemes, there remain persistent inequities in access to the waiting list, allocation of a deceased donor transplant, receiving a living donor transplant and achieving preemptive transplantation. Older age, lower socioeconomic status and health literacy are key factors that continue to impact equity of access to transplantation.

SUMMARY

A number of modifiable factors have been identified affecting access to transplantation, Increased patient education together with a better access to and promotion of living donation may help address some of these inequities.

摘要

目的综述:与透析治疗相比,肾移植可为终末期肾病(ESRD)患者提供更长、更健康和更高质量的生活机会。在移植途径的多个环节都存在不平等现象。在这篇综述中,我们将从欧洲的角度探讨导致肾移植机会不平等的因素。

最近的发现:尽管在患者评估和器官供应方案的修订方面有所改进,但在进入候补名单、分配已故供体移植、接受活体供体移植和实现抢先移植方面,仍存在持续的不平等现象。年龄较大、社会经济地位较低和健康素养是继续影响移植机会公平性的关键因素。

总结:已经确定了一些可改变的因素会影响到接受移植的机会,增加患者教育,以及更好地获取和促进活体捐献,可能有助于解决其中的一些不平等问题。

相似文献

1
Equity of access to renal transplantation: a European perspective.平等获得肾移植机会:欧洲视角。
Curr Opin Organ Transplant. 2021 Aug 1;26(4):347-352. doi: 10.1097/MOT.0000000000000895.
2
Comparing the Net Benefits of Adult Deceased Donor Kidney Transplantation for a Patient on the Preemptive Waiting List vs a Patient Receiving Dialysis.比较预先等待名单上的患者与接受透析治疗的患者进行成人已故供体肾移植的净收益。
JAMA Netw Open. 2022 Jul 1;5(7):e2223325. doi: 10.1001/jamanetworkopen.2022.23325.
3
The experiences of adults who are on dialysis and waiting for a renal transplant from a deceased donor: a systematic review.接受透析治疗并等待已故捐赠者肾脏移植的成年人的经历:一项系统综述。
JBI Database System Rev Implement Rep. 2015 Mar 12;13(2):169-211. doi: 10.11124/jbisrir-2015-1973.
4
Association Between Declined Offers of Deceased Donor Kidney Allograft and Outcomes in Kidney Transplant Candidates.接受或拒绝已故供体肾移植与肾移植候选人结局的关系。
JAMA Netw Open. 2019 Aug 2;2(8):e1910312. doi: 10.1001/jamanetworkopen.2019.10312.
5
Racial and ethnic differences in pediatric access to preemptive kidney transplantation in the United States.美国儿科人群优先接受肾移植机会的种族和民族差异。
Am J Transplant. 2013 Jul;13(7):1769-81. doi: 10.1111/ajt.12299. Epub 2013 Jun 3.
6
A new approach for measuring gender disparity in access to renal transplantation waiting lists.一种衡量肾移植等待名单上获取机会性别差异的新方法。
Transplantation. 2012 Sep 15;94(5):513-9. doi: 10.1097/TP.0b013e31825d156a.
7
Obesity and gender-biased access to deceased donor kidney transplantation.肥胖与性别偏见对接受已故供体肾移植的影响。
Nephrol Dial Transplant. 2020 Jan 1;35(1):184-189. doi: 10.1093/ndt/gfz100.
8
Preemptive transplantation and the transplant first initiative.抢先移植和移植优先倡议。
Curr Opin Nephrol Hypertens. 2010 Nov;19(6):592-7. doi: 10.1097/MNH.0b013e32833e04f5.
9
Factors that influence access to the national renal transplant waiting list.影响进入全国肾移植等候名单的因素。
Transplantation. 2009 Jul 15;88(1):96-102. doi: 10.1097/TP.0b013e3181aa901a.
10
Impact of gender on access to the renal transplant waiting list for pediatric and adult patients.性别对儿科和成年患者进入肾移植等候名单的影响。
J Am Soc Nephrol. 2000 May;11(5):958-964. doi: 10.1681/ASN.V115958.

引用本文的文献

1
Comparison of outcomes after living and deceased donor kidney transplantation: UK national cohort study.活体与 deceased 供体肾移植术后结局比较:英国全国队列研究。 注:这里“deceased”常见释义为“已故的”“死亡的” ,在医学领域结合语境可理解为“尸体供体” 。
Br J Surg. 2025 Aug 1;112(8). doi: 10.1093/bjs/znaf162.
2
Gender disparities in kidney replacement therapies and transplantation in Colombia.哥伦比亚肾脏替代治疗和移植中的性别差异。
BMC Nephrol. 2024 Feb 26;25(1):70. doi: 10.1186/s12882-024-03492-3.
3
Mitigating Health Disparities in Transplantation Requires Equity, Not Equality.
减轻移植中的健康不平等需要公平,而不是平等。
Transplantation. 2024 Jan 1;108(1):100-114. doi: 10.1097/TP.0000000000004630. Epub 2023 May 5.