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美国-墨西哥边境儿科住院患者再喂养综合征的发生率。

Incidence of Refeeding Syndrome in Pediatric Inpatients at the US-Mexico Border.

机构信息

From the Paul L. Foster School of Medicine, Texas Tech University Health Science Center at El Paso, El Paso.

出版信息

South Med J. 2021 Jun;114(6):351-355. doi: 10.14423/SMJ.0000000000001259.

Abstract

OBJECTIVES

Refeeding syndrome is a life-threatening, physiological process that occurs when patients with severe malnutrition are too rapidly rehabilitated, leading to the development of electrolyte abnormalities. Hypophosphatemia, a hallmark of the disease, has most commonly been studied, because it is recognized to result in cardiac arrhythmias, seizures, cardiac failure, respiratory failure, rhabdomyolysis, coma, and even death. Although many studies have found caloric intake to be a main causal factor in refeeding syndrome, few have explored other factors, such as geographic location. Border cities, such as El Paso, Texas, have a unique, diverse population. The purpose of this study was to establish the incidence of refeeding syndrome concentrated within a border city.

METHODS

We performed a retrospective chart review that focused on the incidence of refeeding syndrome in pediatric patients with eating disorders, ages 10 to 19 years, admitted to El Paso Children's Hospital, the only tertiary teaching hospital in the area, associated with Texas Tech University Health Science Center, located along the US-Mexico border, in El Paso, Texas.

RESULTS

Twenty-six subjects with a diagnosis of eating disorder were admitted to El Paso Children's Hospital for treatment between 2012 and 2019. Five subjects developed refeeding syndrome, recognized in our study as hypokalemia or hypomagnesemia, during their treatment.

CONCLUSIONS

Among hospitalized adolescents admitted to El Paso Children's Hospital, 19% developed refeeding syndrome. This incidence was higher in our population than had been previously reported. Further research is needed to better establish a protocol for the treatment of patients with eating disorders.

摘要

目的

再喂养综合征是一种危及生命的生理过程,当严重营养不良的患者过快康复时,会发生这种情况,导致电解质异常。低磷血症是该病的标志,最常被研究,因为它被认为会导致心律失常、癫痫发作、心力衰竭、呼吸衰竭、横纹肌溶解、昏迷,甚至死亡。尽管许多研究发现热量摄入是再喂养综合征的主要原因,但很少有研究探索其他因素,如地理位置。边境城市,如德克萨斯州的埃尔帕索,拥有独特而多样化的人口。本研究的目的是确定集中在边境城市的再喂养综合征的发生率。

方法

我们进行了回顾性图表审查,重点关注在德克萨斯州埃尔帕索的德克萨斯理工大学健康科学中心附属的该地区唯一的三级教学医院埃尔帕索儿童医院就诊的 10 至 19 岁患有饮食失调症的儿科患者中再喂养综合征的发生率。

结果

2012 年至 2019 年间,26 名患有饮食失调症的患者被收入埃尔帕索儿童医院接受治疗。在治疗期间,有 5 名患者出现了再喂养综合征,我们的研究将其定义为低钾血症或低镁血症。

结论

在入住埃尔帕索儿童医院的住院青少年中,有 19%出现了再喂养综合征。我们的人群中的这一发生率高于以前的报告。需要进一步研究以更好地为饮食失调症患者制定治疗方案。

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