不同类型的单绒毛膜双羊膜囊双胎选择性胎儿生长受限的胎盘特点。

Placental characteristics in different types of selective fetal growth restriction in monochorionic diamniotic twins.

机构信息

Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.

出版信息

Acta Obstet Gynecol Scand. 2021 Sep;100(9):1688-1693. doi: 10.1111/aogs.14204. Epub 2021 Jun 29.

DOI:10.1111/aogs.14204

PMID:34075586

Abstract

INTRODUCTION

This study aimed to explore the differences in placental characteristics among three types of selective fetal growth restriction (sFGR) in monochorionic diamniotic twin pregnancies.

MATERIAL AND METHODS

A total of 123 placentas with sFGR between April 2013 and October 2019 were retrospectively analyzed after dye injection. Placental characteristics were compared among the three types.

RESULTS

The gestational age at diagnosis and delivery was less in sFGR II and III than in sFGR I (22.9 [21.7-33.6], 23.3 [20.0-26.1] and 25.7 [19.0-35.0] weeks, p < 0.001; 32.3 [31.6-35.1], 34.1 [29.9-34.7] and 35.5 [34.0-37.0] weeks, p < 0.001). The birthweight discordance ratio was less in sFGR I than in sFGR II (0.28 [0.14-0.43] and 0.30 [0.23-0.37], p < 0.001). The prevalence of a thick artery-artery anastomosis was higher in sFGR III than in sFGR I or II (81.8%, 44.9% and 48.6%, p = 0.010). The placental territory discordance ratio was higher in sFGR II and III than in sFGR I (0.60 [0.17-0.88], 0.60 [0.01-0.80] and 0.50 [0.01-0.71], p = 0.001).

CONCLUSIONS

Compared with sFGR I, the earlier onset time of sFGR II and III might be due to their higher placental territory discordance. The prevalence of thick artery-artery anastomoses was expected to be higher in sFGR III than in sFGR I or II.

摘要

简介

本研究旨在探讨单绒毛膜双羊膜囊双胎妊娠中三种选择性胎儿生长受限（sFGR）的胎盘特征差异。

材料与方法

回顾性分析了 2013 年 4 月至 2019 年 10 月期间经染料注射诊断为 sFGR 的 123 例胎盘。比较了三种类型的胎盘特征。

结果

sFGR II 和 III 的诊断和分娩孕周均较 sFGR I 小（22.9[21.7-33.6]、23.3[20.0-26.1]和 25.7[19.0-35.0]周，p<0.001；32.3[31.6-35.1]、34.1[29.9-34.7]和 35.5[34.0-37.0]周，p<0.001）。sFGR I 的出生体重不匀率较 sFGR II 小（0.28[0.14-0.43]和 0.30[0.23-0.37]，p<0.001）。sFGR III 中厚动脉-动脉吻合的发生率高于 sFGR I 或 II（81.8%、44.9%和 48.6%，p=0.010）。sFGR II 和 III 的胎盘区域不匀率高于 sFGR I（0.60[0.17-0.88]、0.60[0.01-0.80]和 0.50[0.01-0.71]，p=0.001）。