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尼日利亚尼日尔三角洲地区行体外受精术的薄型子宫内膜患者的宫腔镜检查结果。

Hysteroscopy Findings in Women with Thin Endometrium Scheduled for In Vitro fertilization in Niger Delta Region, Nigeria.

机构信息

Assisted Reproduction Unit, Gynescope Specialist Hospital: 22/24 Gynescope Drive Port Harcourt, Rivers State.

出版信息

Afr J Reprod Health. 2020 Jun;24(2):123-128. doi: 10.29063/ajrh2020/v24i2.12.

Abstract

The effect of endometrial thickness on in vitro fertilization (IVF) outcome is still a subject of debate. It is unclear why a thin endometrium reduces IVF success rates. Our objective was to analyze the hysteroscopic findings in women scheduled for IVF who had an endometrial thickness less than 7 mm. Relevant data of patients scheduled for IVF cycles and found to have an endometrial thickness (ET) of <7 mm on transvaginal ultrasound scan (TVS) between April 1, 2010 and March 31, 2017, at a private fertility and minimal access surgery unit in the Niger-Delta region of Nigeria, were retrieved and documented. A total of 41 patients had ET <7 mm during the study period. These patients accounted for 2.8% of the 1487 IVF cycles performed during the same period. All 41 patients had office hysteroscopies performed, constituting 4.1% of the 1,002 hysteroscopies performed during the study period. The age range of the patients was 23 - 50 years with a mean of 39.9 ± 6.9 years, and the duration of infertility ranged from 3 to 13 years with a mean of 7.2 ± 2.5 years. Most of the patients (32, 78.1%) had secondary infertility. Sixteen patients (39.0%) had intrauterine adhesions. A thin endometrium, though infrequent during IVF treatment cycles, might be associated with undiagnosed intrauterine adhesions.

摘要

子宫内膜厚度对体外受精(IVF)结局的影响仍然存在争议。目前尚不清楚为什么薄的子宫内膜会降低 IVF 的成功率。我们的目的是分析在尼日利亚尼日尔三角洲地区的一家私人生育和微创外科单位进行 IVF 周期的女性中,那些子宫内膜厚度(ET)<7 毫米的宫腔镜检查结果。我们检索并记录了 2010 年 4 月 1 日至 2017 年 3 月 31 日期间,因 TVS 发现 ET<7 毫米而计划进行 IVF 周期的患者的相关数据。在研究期间,共有 41 名患者的 ET<7 毫米。这些患者占同期进行的 1487 个 IVF 周期的 2.8%。所有 41 名患者均进行了门诊宫腔镜检查,占同期进行的 1002 次宫腔镜检查的 4.1%。患者的年龄范围为 23-50 岁,平均年龄为 39.9 ± 6.9 岁,不孕持续时间为 3-13 年,平均为 7.2 ± 2.5 年。大多数患者(32 例,78.1%)为继发性不孕。16 例(39.0%)患者有宫腔粘连。尽管在 IVF 治疗周期中很少出现薄的子宫内膜,但它可能与未诊断的宫腔粘连有关。

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