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从 (Pallas,1811)血液中分离出的新型 sp.的基因组特征分析。

Genomic Characterization of the Novel sp. Isolated from the Blood of a (Pallas, 1811).

机构信息

Zoonotic and Vector-Borne Diseases Department, Ministry of Health, General Directorate of Public Health, Ankara, Turkey.

UMR VITROME, Aix-Marseille University, Institut pour la Recherche et le Développement, Service de Santé des Armées, Assistance Publique-Hôpitaux de Marseille, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.

出版信息

Vector Borne Zoonotic Dis. 2021 Jun;21(6):432-440. doi: 10.1089/vbz.2020.2626. Epub 2020 Jun 16.

DOI:10.1089/vbz.2020.2626
PMID:34077294
Abstract

species are reemerging infectious agents that are transmitted by arthropod vectors among animals and/or humans. At least 13 of the 35 currently recognized species are pathogenic for humans. Most of the pathogenic species, except and are zoonotic agents with animal reservoirs, including cats, dogs, coyotes, foxes, cattle, and rodents. In this study, a novel species was isolated from the blood of a (Pallas, 1811) Lesser shrew that was captured in the Bartın region of Northwestern Turkey. The strain, RSKK 19006, was characterized using whole-genome sequencing and comparison, multilocus sequence typing ( and 16S rRNA) and internal transcribed spacer sequencing, electron microscopy scanning, biochemical tests, and MALDI-TOF MS (matrix assisted laser desorption ionization-time of flight mass spectrometry). This novel is a Gram-negative, rod-shaped, microaerophilic bacterium and has neither flagella nor pilus. As a consequence, we propose to name this new species sp. nov. in genus. The zoonotic potential of this novel species is as yet unknown.

摘要

种是通过节肢动物媒介在动物和/或人类之间传播的再现传染病原体。目前已确认的 35 种中至少有 13 种对人类具有致病性。除 和 外,大多数致病性种是具有动物宿主的人畜共患病原体,包括猫、狗、郊狼、狐狸、牛和啮齿动物。在这项研究中,从在土耳其西北部 Bartın 地区捕获的一只(Pallas,1811)小鼩鼱的血液中分离到了一种新型 种。该菌株 RSKK 19006 是通过全基因组测序和比较、多位点序列分型(和 16S rRNA)和内部转录间隔区测序、电子显微镜扫描、生化试验和 MALDI-TOF MS(基质辅助激光解吸电离飞行时间质谱)进行表征的。这种新型 是一种革兰氏阴性、杆状、微需氧细菌,既没有鞭毛也没有菌毛。因此,我们建议将这种新的种命名为属中的 sp. nov.。这种新型 种的人畜共患潜力尚不清楚。

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