Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
McGovern Medical School, Houston, TX, USA.
Aesthet Surg J. 2021 Sep 14;41(10):NP1303-NP1309. doi: 10.1093/asj/sjab235.
The use of autologous fat grafting (AFG) is becoming increasingly common as an adjunct to breast reconstruction. However, there is a paucity of data comparing the varying processing devices.
The goal of this study was to compare the outcomes of 2 commercially available AFG processing devices.
A retrospective review was conducted of patients who underwent AFG with dual-filter (Puregraft) or single-filter (Revolve) processing systems between 2016 and 2019. Propensity score matching was utilized to adjust for confounding. A total of 38 breasts from the Puregraft group were matched with 38 breasts from the Revolve group.
Matching was successful in achieving a similar distribution of baseline characteristics between the 2 groups. The mean number of AFG sessions was comparable between the 2 groups (P = 0.37) with a similar median total volume (Puregraft, 159 mL vs Revolve, 130 mL; P = 0.23). Complication rates were similar between the 2 devices (Puregraft, 26%; Revolve, 18%; P = 0.47). Patients with at least 1 complication had higher overall AFG volume (median, 200 mL vs 130 mL; P = 0.03) and number of sessions (mean, 2.4 vs 1.8, P = 0.009) compared with those without any postoperative complication.
Overall complication rates were comparable between 2 commonly used, commercially available AFG processing systems, and therefore the choice of which to use should be based on surgeon preference. Future studies are underway to decipher whether either system offers superior graft retention, cosmetic, or patient-reported outcomes.
自体脂肪移植（AFG）作为乳房重建的辅助手段越来越普遍。然而，比较不同处理设备的数据却很少。
本研究旨在比较两种市售 AFG 处理设备的结果。
对 2016 年至 2019 年间接受双滤过（Puregraft）或单滤过（Revolve）处理系统 AFG 的患者进行回顾性研究。采用倾向评分匹配法调整混杂因素。Puregraft 组的 38 个乳房与 Revolve 组的 38 个乳房进行匹配。
匹配成功地使两组之间的基线特征分布相似。两组之间的 AFG 治疗次数相似（P=0.37），总容量中位数也相似（Puregraft，159ml 比 Revolve，130ml；P=0.23）。两种设备的并发症发生率相似（Puregraft，26%；Revolve，18%；P=0.47）。至少有 1 种并发症的患者总 AFG 体积（中位数，200ml 比 130ml；P=0.03）和治疗次数（平均，2.4 比 1.8，P=0.009）均高于无术后并发症的患者。
两种常用的市售 AFG 处理系统的总体并发症发生率相似，因此应根据外科医生的偏好选择使用哪种系统。目前正在进行进一步的研究，以确定这两种系统中的任何一种是否具有更好的移植物保留、美容或患者报告的结果。
