Hue Hye Jeong, Choi Hyun Ji, Park Jee Yoon, Suh Dong Hoon, Lee Jung Ryeol, Jee Byung Chul, Kim Seul Ki
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
Clin Exp Reprod Med. 2021 Jun;48(2):184-187. doi: 10.5653/cerm.2020.04070. Epub 2021 May 25.
Radical trachelectomy is a fertility-preserving alternative to radical hysterectomy in carefully selected young women with early-stage cervical cancer. However, in cases with subsequent severe cervical stenosis, assisted reproductive techniques can be difficult. This is a case report of a 34-year-old patient who underwent robot-assisted radical trachelectomy and cerclage for early-stage (IB2) adenosquamous carcinoma. Three months after surgery, the patient underwent ovarian stimulation using a gonadotropin-releasing hormone antagonist protocol. As it was impossible to perform transcervical embryo transfer due to the almost complete absence of the cervical opening, transmyometrial embryo transfer under ultrasound guidance was performed. This resulted in a successful singleton pregnancy. This is the first case of successful pregnancy conceived by in vitro fertilization with transmyometrial embryo transfer in a patient who had previously undergone robot-assisted radical trachelectomy.
根治性宫颈切除术是为精心挑选的早期宫颈癌年轻女性保留生育能力的一种替代根治性子宫切除术的方法。然而,在随后出现严重宫颈狭窄的情况下,辅助生殖技术可能会遇到困难。本文报告一例34岁患者,因早期(IB2期)腺鳞癌接受了机器人辅助根治性宫颈切除术和宫颈环扎术。术后三个月,患者采用促性腺激素释放激素拮抗剂方案进行卵巢刺激。由于宫颈开口几乎完全消失,无法进行经宫颈胚胎移植,遂在超声引导下进行经肌层胚胎移植。这导致了单胎妊娠成功。这是首例在先前接受机器人辅助根治性宫颈切除术的患者中通过体外受精经肌层胚胎移植成功受孕的病例。