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腺病毒感染与横纹肌溶解作为一名健康大学橄榄球运动员急性肝衰竭的病因:病例报告及横纹肌溶解后拟议的重返比赛方案

Adenovirus Infection and Rhabdomyolysis as a Cause of Acute Liver Failure in a Healthy Collegiate Football Athlete: A Case Report and Proposed Return to Play Protocol for Rhabdomyolysis.

作者信息

Hwang Calvin E, Matheson Gordon, Baine Jennifer

机构信息

Orthopaedic Surgery, Stanford University, Stanford, USA.

Sports Medicine, Stanford University, Stanford, USA.

出版信息

Cureus. 2021 Apr 15;13(4):e14510. doi: 10.7759/cureus.14510.

DOI:10.7759/cureus.14510
PMID:34079658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8159334/
Abstract

Adenovirus is a common cause of upper respiratory and gastrointestinal tract infections. Though cases of significant organ failure and death have been reported in young children and immunocompromised individuals, adenovirus infections in healthy individuals are typically self-limiting without significant morbidity or mortality. Exertional rhabdomyolysis is a pathologic condition resulting from repetitive, excessive, or prolonged exercise, often in a hot environment, leading to acute muscle injury, renal injury and, rarely, death. We report a case of adenovirus infection leading to acute liver failure complicated by rhabdomyolysis in a collegiate football player presenting with nausea, vomiting, and diarrhea. We propose a protocol to safely guide the return to play progression for patients with complicated exertional rhabdomyolysis.

摘要

腺病毒是上呼吸道和胃肠道感染的常见病因。尽管在幼儿和免疫功能低下个体中已报告有严重器官衰竭和死亡病例,但健康个体中的腺病毒感染通常为自限性,不会导致显著的发病率或死亡率。运动性横纹肌溶解是一种病理状况,通常由在炎热环境中重复、过度或长时间运动引起,导致急性肌肉损伤、肾损伤,很少导致死亡。我们报告了一例腺病毒感染导致急性肝衰竭并伴有横纹肌溶解的病例,该病例为一名大学橄榄球运动员,表现为恶心、呕吐和腹泻。我们提出了一项方案,以安全指导患有复杂运动性横纹肌溶解症的患者恢复运动进程。

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本文引用的文献

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Abnormal liver function tests associated with severe rhabdomyolysis.肝功能异常与严重横纹肌溶解症相关。
World J Gastroenterol. 2020 Mar 14;26(10):1020-1028. doi: 10.3748/wjg.v26.i10.1020.
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Return to Play After Exertional Rhabdomyolysis.运动性横纹肌溶解症后的重返运动
J Athl Train. 2016 May;51(5):406-9. doi: 10.4085/1062-6050-51.5.12. Epub 2016 May 17.
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Creatine kinase levels during preseason camp in National Collegiate Athletic Association Division I football athletes.美国国家大学体育协会第一分区橄榄球运动员季前训练营期间的肌酸激酶水平。
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