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尿流改道与代谢性酸中毒:一例报告

Urinary Diversion and Metabolic Acidosis: A Case Report.

作者信息

Dsouza Landric B, Hussein Rana Jaffer H

机构信息

Emergency Department, Hamad Medical Corporation, Doha, QAT.

出版信息

Cureus. 2021 Apr 22;13(4):e14638. doi: 10.7759/cureus.14638.

DOI:10.7759/cureus.14638
PMID:34079665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8159343/
Abstract

Urinary diversion, a surgical technique to redirect urine usually after cystectomy, and its complications are potential challenges to physicians and early recognition decreases mortality and morbidity. A 45-year-old male with a history of type 2 diabetes mellitus and hypertension for over three years underwent urinary diversion as a treatment for invasive bladder cancer and was discharged ambulatory with an indwelling Foleys catheter. The patient returned to the emergency room with a primary complaint of hematuria. The patient was noted to be frail-looking, dehydrated and tachycardic. Laboratory results yielded an acute kidney injury reflected by the elevated creatinine, hyperkalemia and a venous blood gas demonstrating a hyperchloremic metabolic acidosis. The patient had bilateral distended renal calyces by ultrasound and irrigation of bladder through a three-way Foley showed to have large thick clots. The patient was admitted under the surgical intensive care unit after involving appropriate sub-specialties. The patient was started on sodium bicarbonate infusion, broad-spectrum antibiotics and a urinary catheter in place to monitor urine output. The patient's acidosis steadily improved with correction of his laboratory parameters, transferred out of ICU and the remaining stay in the medical ward was uneventful. The purpose of this case report is to help demonstrate the association between urinary diversion and the type of acidosis that subsequently develops in relation to this surgical procedure.

摘要

尿流改道术是一种通常在膀胱切除术后用于重新引导尿液的外科技术,其并发症对医生来说是潜在的挑战,而早期识别可降低死亡率和发病率。一名45岁男性,有2型糖尿病和高血压病史超过三年,因浸润性膀胱癌接受尿流改道术治疗,出院时携带留置的Foley导管可自行活动。该患者因血尿为主诉返回急诊室。患者看起来虚弱、脱水且心动过速。实验室检查结果显示急性肾损伤,表现为肌酐升高、高钾血症,静脉血气分析显示高氯性代谢性酸中毒。超声检查显示患者双侧肾盏扩张,通过三腔Foley导管冲洗膀胱发现有大量粗大血块。在相关亚专业会诊后,患者被收入外科重症监护病房。开始给患者输注碳酸氢钠、使用广谱抗生素并留置导尿管以监测尿量。随着实验室指标的纠正,患者的酸中毒情况逐渐改善,转出重症监护病房,在普通内科病房的剩余住院期间病情平稳。本病例报告的目的是帮助证明尿流改道术与该手术相关的后续发生的酸中毒类型之间的关联。

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Urinary Diversion and Metabolic Acidosis: A Case Report.尿流改道与代谢性酸中毒:一例报告
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An unrecognised case of metabolic acidosis following neobladder augmentation cystoplasty.新膀胱扩大膀胱成形术后一例未被识别的代谢性酸中毒病例。
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[Results of radical cystectomy for management of invasive bladder cancer with special reference to prognostic factors and quality of life depending on the type of urinary diversion].[根治性膀胱切除术治疗浸润性膀胱癌的结果,特别提及根据尿流改道类型的预后因素和生活质量]
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[A case of metabolic acidosis and tetany after ileal neobladder replacement].[回肠新膀胱置换术后代谢性酸中毒和手足搐搦1例]
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[Hyperchloremic metabolic acidosis after ileal conduit reconstruction: a case report].回肠代膀胱术后高氯性代谢性酸中毒:一例报告
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Association between Development of Metabolic Acidosis and Improvement of Urinary Continence after Ileal Neobladder Creation.代谢性酸中毒的发展与回肠新膀胱术后尿控改善的关系。
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引用本文的文献

1
Hypokalaemic quadriparesis in a patient with urinary diversion through Indiana pouch.经 Indiana 袋行尿路转流术的患者出现低钾性四肢瘫痪。
BMJ Case Rep. 2022 Apr 29;15(4):e248123. doi: 10.1136/bcr-2021-248123.

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Acid-base changes following urinary tract reconstruction for continent diversion and orthotopic bladder replacement.用于可控性尿流改道和原位膀胱替代的尿路重建术后的酸碱变化。
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