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一名艾滋病患者罕见硅瘤的诊断与管理

Diagnosis and Management of Rare Siliconomas in an HIV Patient.

作者信息

Munagala Rohit, Mishra Pranjal, Chakravartty Akash, Bhatt Arjun N, Keshavamurthy Jayanth

机构信息

Radiology, Augusta University Medical College of Georgia, Augusta, USA.

出版信息

Cureus. 2021 Apr 23;13(4):e14645. doi: 10.7759/cureus.14645.

DOI:10.7759/cureus.14645
PMID:34079666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8159319/
Abstract

Siliconomas are rare conditions stemming from uses of silicone injections for soft tissue augmentation, most commonly in the breast and buttocks areas. Siliconomas are known to present with suspicious morphology that mimics cases of embolism or systemic metastasis as the silicone travels through blood and lymphatics. We present the case of a 45-year-old HIV-positive male who presented with siliconomas in the breast region, chest heaviness, shortness of breath, dyspnea, and a physical exam showing gynecomastia. The patient denied any surgeries or injections around his chest. Further imaging showed abnormal fat deposition in the chest and possible metastatic lymphadenopathy to axillary, supraclavicular, and mammillary lymph nodes. Although the complications arising from silicone injections are well documented, the pathogenesis remains unknown, leaving a narrow range of therapeutic options. Despite these shortcomings, diagnostic imaging tools have shown to be vital in the diagnosis and localization of suspected siliconomas.

摘要

硅瘤是一种罕见的病症,源于使用硅胶注射进行软组织填充,最常见于乳房和臀部区域。已知硅瘤会呈现出可疑的形态,因为硅胶通过血液和淋巴管流动时,会模仿栓塞或全身转移的病例。我们报告一例45岁的HIV阳性男性病例,该患者乳房区域出现硅瘤,伴有胸部沉重感、呼吸急促、呼吸困难,体格检查显示有男性乳房发育。患者否认胸部周围有任何手术或注射史。进一步的影像学检查显示胸部脂肪沉积异常,腋窝、锁骨上和乳头淋巴结可能有转移性淋巴结病。尽管硅胶注射引起的并发症已有充分记录,但其发病机制仍然未知,治疗选择范围狭窄。尽管存在这些缺点,但诊断成像工具已被证明在疑似硅瘤的诊断和定位中至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/2c51280a6b6c/cureus-0013-00000014645-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/6a9ec6420ffb/cureus-0013-00000014645-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/c656483f1137/cureus-0013-00000014645-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/2c51280a6b6c/cureus-0013-00000014645-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/6a9ec6420ffb/cureus-0013-00000014645-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/c656483f1137/cureus-0013-00000014645-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6c4/8159319/2c51280a6b6c/cureus-0013-00000014645-i03.jpg

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Presentation and Management of Silicone Lymphadenopathy: A Single Institutional Retrospective Cohort Study.硅胶所致淋巴结病的临床表现与管理:一项单机构回顾性队列研究
Aesthetic Plast Surg. 2025 Jan 10. doi: 10.1007/s00266-024-04649-z.

本文引用的文献

1
Siliconomas of the lower limb: Tumour-like excision and reconstruction.下肢硅瘤:肿瘤样切除与重建。
Indian J Plast Surg. 2016 Sep-Dec;49(3):384-389. doi: 10.4103/0970-0358.197228.
2
Siliconoma of the breasts.乳房硅瘤
Gland Surg. 2013 Feb;2(1):46-9. doi: 10.3978/j.issn.2227-684X.2013.02.05.
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Silicone injections.硅酮注射
J Cutan Aesthet Surg. 2012 Jul;5(3):197.
4
Medical-grade fluid silicone. A monographic review.医用级液体硅酮。专题综述。
J Dermatol Surg Oncol. 1977 Nov-Dec;3(6):597-611. doi: 10.1111/j.1524-4725.1977.tb00366.x.