Martin D H, Bianchi E, Ben Mustapha S, Frères P
Service de Neurochirurgie, CHU Liège, Belgique.
Service d'Anatomie et Cytologie pathologiques, CHU Liège, Belgique.
Rev Med Liege. 2021 May;76(5-6):419-424.
Glioblastoma is the most common primary malignant brain tumor. Despite treatments combining excisional surgery, chemotherapy, and radiotherapy, overall survival remains low and the incidence of tumor recurrence remains high. Advances in the understanding of the disease, particularly its molecular biology and the mechanisms of action of systemic and radiotherapeutic treatments, as well as the development of image-guided surgical techniques, offer hope for the control of this hitherto incurable disease.
胶质母细胞瘤是最常见的原发性恶性脑肿瘤。尽管采用了手术切除、化疗和放疗相结合的治疗方法，但总体生存率仍然很低，肿瘤复发率仍然很高。对该疾病认识的进展，特别是其分子生物学以及全身治疗和放射治疗的作用机制，以及图像引导手术技术的发展，为控制这种迄今为止无法治愈的疾病带来了希望。
