Center for Biobehavioral Health, 2650Nationwide Children's Hospital, Columbus, OH, USA.
2331University of North Carolina at Chapel Hill Hospitals, Chapel Hill, NC, USA.
Prog Transplant. 2021 Jun;31(2):108-116. doi: 10.1177/15269248211002809.
Living donor transplantation of kidneys accounts for one quarter of transplants performed in the United States. Careful screening of psychiatric history is a standard part of the donor evaluation. Little is known about the impact of psychiatric history on post-donation course and pain experience.
This study investigated whether psychiatric history was associated with pain and related outcomes among living kidney donors.
A retrospective medical record review was conducted of 75 living kidney donors who underwent laparoscopic donor nephrectomy. All donor candidates completed a psychological evaluation and were approved for donation by a multidisciplinary committee. History of psychiatric diagnosis and psychiatric medication use were obtained from donors' psychological evaluation reports. Data on pain and related outcomes (ie, history of prescribed pain medication, post-donation pain, opioid use, length of hospital stay, post-donation emergency department visits), as well as demographic and donation-related characteristics were also abstracted from medical records.
Psychiatric history, including current or historical psychiatric diagnosis or psychiatric medication use, in living kidney donors who were evaluated and approved for donation by a transplant psychologist was not associated with greater perceived pain, greater use of opioid pain medication in the post-operative period, longer hospital stays, or more frequent post-donation emergency department visits.
The findings demonstrate that carefully screened donors with a psychiatric history have comparable pain-related outcomes as donors without a psychiatric history. This study highlights the importance of the pre-donation psychological evaluation in promoting positive postdonation outcomes through careful selection of donor candidates.
在美国进行的移植手术中,有四分之一是活体器官捐献者进行的。对精神病史进行仔细筛查是供体评估的标准组成部分。对于精神病史对捐赠后过程和疼痛体验的影响知之甚少。
本研究调查了精神病史是否与活体肾供者的疼痛及相关结果有关。
对 75 名接受腹腔镜供肾切除术的活体肾供者进行了回顾性病历回顾。所有供体候选人都完成了心理评估,并通过多学科委员会批准供体。从供体的心理评估报告中获得了精神病史诊断和精神科药物使用的历史。从病历中还提取了与疼痛和相关结果(即规定的止痛药物使用史、捐赠后疼痛、阿片类药物使用、住院时间、捐赠后急诊就诊)有关的数据,以及人口统计学和捐赠相关特征。
接受移植心理学家评估和批准的活体肾供者有精神病史,包括当前或既往的精神科诊断或精神科药物使用史,与感知疼痛程度更大、术后使用阿片类止痛药更多、住院时间更长或捐赠后急诊就诊更频繁无关。
研究结果表明,经过仔细筛选的有精神病史的供者与没有精神病史的供者具有相似的疼痛相关结局。本研究强调了在通过仔细选择供体候选人来促进积极的捐赠后结果的情况下,预捐赠心理评估的重要性。