University of Washington, Division of General Internal Medicine, Department of Medicine, 325 9th Avenue, Seattle, WA 98104, USA.
Public Health-Seattle & King County, HIV/STD Program, 401 Fifth Ave, Suite 1250, Seattle, WA 98104, USA; University of Washington, Division of Allergy and Infectious Diseases, Department of Medicine, 325 9th Avenue, Box 359777, Seattle, WA 98104, USA.
J Subst Abuse Treat. 2021 Oct;129:108375. doi: 10.1016/j.jsat.2021.108375. Epub 2021 Mar 19.
To describe utilization patterns of methadone and buprenorphine among persons who inject drugs (PWID) in the Seattle area in 2018, compared to 2015.
Data from the 2018 National HIV Behavioral Surveillance (NHBS) system were used to compare the proportions of PWID reporting treatment with buprenorphine or methadone to survey responses in 2015. Temporal trends were assessed by calculating adjusted prevalence ratios (aPR) using Poisson regression.
The sample included 498 PWID, of whom 39.2% (95% CI: 34.8-43.6%) reported past-year treatment with methadone and 21.9% (95% CI: 18.3-25.8%) reported buprenorphine. Participants in 2018 were significantly more likely to report past year receipt of buprenorphine (aPR = 4.43, 95% CI: 2.81-7.01) or methadone (aPR = 1.38, 95% CI: 1.02-1.87) compared to 2015. Most buprenorphine treated participants (67.6%) reported that they had received buprenorphine through low-barrier, community, or nonprofit programs.
Among PWID who use opioids in the Seattle area, methadone use increased 38%, and buprenorphine use more than quadrupled from 2015 to 2018. Approximately half of surveyed PWID who use opioids still reported no treatment with either medication, highlighting remaining treatment gaps.
描述 2018 年西雅图地区注射吸毒者(PWID)与 2015 年相比,美沙酮和丁丙诺啡的使用模式。
利用 2018 年国家艾滋病毒行为监测(NHBS)系统的数据,比较报告接受丁丙诺啡或美沙酮治疗的 PWID 比例与 2015 年调查结果。使用泊松回归计算调整后流行率比(aPR)评估时间趋势。
样本包括 498 名 PWID,其中 39.2%(95%CI:34.8-43.6%)报告过去一年接受美沙酮治疗,21.9%(95%CI:18.3-25.8%)报告丁丙诺啡治疗。与 2015 年相比,2018 年参与者更有可能报告过去一年接受丁丙诺啡(aPR=4.43,95%CI:2.81-7.01)或美沙酮(aPR=1.38,95%CI:1.02-1.87)治疗。大多数接受丁丙诺啡治疗的参与者(67.6%)报告说,他们通过低门槛、社区或非营利计划接受了丁丙诺啡治疗。
在西雅图地区使用阿片类药物的 PWID 中,美沙酮使用增加了 38%,而丁丙诺啡使用从 2015 年到 2018 年增加了四倍多。大约一半接受调查的使用阿片类药物的 PWID 仍未接受任何药物治疗,突出了仍存在的治疗差距。