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社区超声心动图心脏重构指标的预后意义。

Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community.

机构信息

Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA, 01702, USA.

Sections of Preventive Medicine and Epidemiology, and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.

出版信息

Curr Cardiol Rep. 2021 Jun 3;23(7):86. doi: 10.1007/s11886-021-01512-4.

Abstract

PURPOSE OF REVIEW

Echocardiography is a noninvasive tool of choice for evaluating cardiac structure and function in numerous cardiac conditions ranging from congenital heart disease, myocardial diseases, coronary artery disease (CAD), valvulopathies, arrhythmias, and pericardial disorders. We review the prognostic significance of echocardiographic indices of cardiac remodeling in the general population.

RECENT FINDINGS

Recent meta-analyses have confirmed the prognostic significance of echocardiographic measurements (left ventricular mass/hypertrophy, systolic and diastolic dysfunction, left atrial dimensions and function, and strain rate measures) in asymptomatic people in the community for adverse clinical outcomes including CAD, stroke, heart failure, atrial fibrillation, sudden death, and all-cause mortality. The clinical utility of screening echocardiography has been examined comprehensively in hypertensive patients, where it is challenged by measurement variability. Echocardiographic measures predict cardiovascular disease outcomes consistently in multiple community-based epidemiological studies. However, the clinical utility of screening asymptomatic individuals with echocardiography in population-based settings is limited.

摘要

目的综述

超声心动图是一种非侵入性的工具,可用于评估从先天性心脏病、心肌疾病、冠状动脉疾病(CAD)、瓣膜病、心律失常和心包疾病等多种心脏疾病的心脏结构和功能。我们综述了心脏重构的超声心动图指标在普通人群中的预后意义。

最近的发现

最近的荟萃分析证实了超声心动图测量(左心室质量/肥大、收缩和舒张功能障碍、左心房大小和功能以及应变率测量)在社区无症状人群中的预后意义,这些人群的不良临床结局包括 CAD、中风、心力衰竭、心房颤动、猝死和全因死亡率。高血压患者中全面检查了筛查超声心动图的临床实用性,但其受到测量变异性的挑战。超声心动图测量在多个基于社区的流行病学研究中一致预测心血管疾病结局。然而,在基于人群的环境中使用超声心动图筛查无症状个体的临床实用性有限。

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