Department of Medical Oncology, Istanbul University-Cerrahpasa Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
J Med Virol. 2021 Oct;93(10):5839-5845. doi: 10.1002/jmv.27123. Epub 2021 Jun 12.
Undoubtedly, cancer patients have suffered the most from the COVID-19 pandemic process. However, cancer is a heterogeneous disease, and each patient has responded differently to COVID-19. We aimed to describe the clinical characteristics and outcomes of patients with cancer and COVID-19. We retrospectively reviewed 45 cancer patients hospitalized in the Cerrahpaşa Medical Faculty COVID-19 department from March 23 to October 23, 2020. We analyzed the demographic characteristics, symptoms, laboratory findings, treatment, prognosis, and cancer subtypes of patients and mortality who were hospitalized for COVID-19. Between March 23 and October 23, 2020, 45 hospitalized cancer patients who had laboratory-confirmed COVID-19 infection were included, with a median age of 60 years (range: 23-92). Patients were divided into two groups a survivor and a non-survivor. Symptoms, demographic information, comorbidities, treatments for COVID-19, and laboratory findings of the two groups were evaluated separately. Two parameters were found, which showed a significant difference between non-survivors and survivors displaying a disadvantage for COPD and low platelet count (p = 0.044-0.038). The mortality rate of all patients was 66%. The presence of comorbidities such as COPD and low platelet count in cancer patients with COVID-19 infection may draw the attention of physicians.
毫无疑问,癌症患者在 COVID-19 大流行过程中遭受的苦难最多。然而,癌症是一种异质性疾病,每个患者对 COVID-19 的反应都不同。我们旨在描述癌症和 COVID-19 患者的临床特征和结局。我们回顾性分析了 2020 年 3 月 23 日至 10 月 23 日期间在 Cerrahpaşa 医科大学 COVID-19 科住院的 45 例癌症患者。我们分析了患者的人口统计学特征、症状、实验室发现、治疗、预后和癌症亚型以及因 COVID-19 住院的死亡率。在 2020 年 3 月 23 日至 10 月 23 日期间,共纳入了 45 例经实验室确诊 COVID-19 感染的住院癌症患者,中位年龄为 60 岁(范围:23-92 岁)。患者分为幸存者和非幸存者两组。分别评估了两组的症状、人口统计学信息、合并症、COVID-19 治疗和实验室发现。有两个参数在非幸存者和幸存者之间显示出显著差异,对 COPD 和血小板计数低显示不利(p=0.044-0.038)。所有患者的死亡率为 66%。在 COVID-19 感染的癌症患者中存在 COPD 和血小板计数低等合并症可能会引起医生的注意。