Grant I R, Parsons S W, Johnstone J M, Wood J K
Department of Haematology, Leicester Royal Infirmary.
Ann R Coll Surg Engl. 1988 Jan;70(1):29-33.
We report on 106 elective splenectomies performed for haematological disorders between March 1979 and January 1986. The most common indications were immune thrombocytopenic purpura (30 patients) and Hodgkin's disease (19 patients). However, staging laparotomy is no longer performed routinely for patients with Hodgkin's disease and the reasons for this are discussed. Other indications for splenectomy included splenic pain (13 patients), autoimmune haemolytic anaemia (12 patients), hereditary spherocytosis (11 patients) and hypersplenism (9 patients). The overall morbidity and mortality was 48% and 5% respectively. The most common postoperative complication was thrombocytosis (defined as a platelet count greater than 800 X 10(9)/l) and occurred in 26 patients. This review confirms that splenectomy continues to have an important role in the management of certain haematological disorders.
我们报告了1979年3月至1986年1月期间因血液系统疾病行择期脾切除术的106例患者。最常见的适应证是免疫性血小板减少性紫癜（30例）和霍奇金病（19例）。然而，霍奇金病患者不再常规进行分期剖腹探查术，并对此原因进行了讨论。脾切除术的其他适应证包括脾区疼痛（13例）、自身免疫性溶血性贫血（12例）、遗传性球形红细胞增多症（11例）和脾功能亢进（9例）。总体发病率和死亡率分别为48%和5%。最常见的术后并发症是血小板增多症（定义为血小板计数大于800×10⁹/L），26例患者发生该并发症。本综述证实，脾切除术在某些血液系统疾病的治疗中仍具有重要作用。
