Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan.
Cancer. 2021 Sep 15;127(18):3437-3444. doi: 10.1002/cncr.33646. Epub 2021 Jun 3.
Patients with cancer have played a key role in advocating for legal access to cannabis, but little is known about links between cancer and cannabis use or cannabis-related beliefs. The authors used data from a national survey to study these relationships.
Nationally representative data collected by the National Survey on Drug Use and Health from 2015 to 2019 were acquired. Patterns of cannabis use and cancer history were examined and tested within age group subpopulations via domain analysis using survey weights.
Data for 214,505 adults, including 4741 individuals (3.8%) with past (>1 year ago) cancer diagnosis and 1518 individuals (1.2%) with recent (≤1 year ago) cancer diagnosis, were examined. Cannabis use was less common in those with past (8.9%; 95% CI, 8.0%-9.8%) or recent (9.9%; 95% CI, 6.9%-11.1%) cancer diagnosis than in those without a history of cancer (15.9%; 95% CI, 15.7%-16.1%). However, when analyses were stratified by age group, those 18 to 34 years of age were more likely to report past cannabis use, and those 35 to 49 years of age were more likely to report past or recent cannabis use if they had a history of cancer. Younger patients felt that cannabis was more accessible and less risky if they had a history of cancer.
Patients with cancer were less likely to report cannabis use, but there were different cannabis perceptions and use patterns by age. Age should be considered in studies of cannabis and cancer, and policy initiatives may be needed to aid provision of quality information on cannabis risk to those with cancer.
Cannabis (marijuana) use is increasing in the United States, but we do not have much information on the relationship between cannabis use and cancer. We studied information from a representative group of people and found that younger patients generally reported more past and/or recent cannabis use if they had been diagnosed with cancer whereas older individuals did not. Beliefs about cannabis risk and accessibility differed by age. Clinical trials to study cannabis should account for patient age, and accurate information about cannabis should be provided to help patients with cancer make decisions about cannabis use.
癌症患者在倡导合法获取大麻方面发挥了关键作用，但对于癌症与大麻使用或与大麻相关的信念之间的联系知之甚少。作者利用全国性调查的数据研究了这些关系。
获取了 2015 年至 2019 年国家药物使用和健康调查收集的全国代表性数据。通过使用调查权重进行域分析，在年龄组亚群中检查和测试了大麻使用模式和癌症病史。
共检查了 214505 名成年人的数据，其中包括 4741 名（3.8%）过去（>1 年前）诊断出癌症的个体和 1518 名（1.2%）最近（≤1 年前）诊断出癌症的个体。过去（8.9%；95%CI，8.0%-9.8%）或最近（9.9%；95%CI，6.9%-11.1%）诊断出癌症的个体中，大麻使用的比例较低，而没有癌症病史的个体中，大麻使用的比例为 15.9%（95%CI，15.7%-16.1%）。然而，当按年龄组分层分析时，18 至 34 岁的人更有可能报告过去使用过大麻，如果他们有癌症病史，35 至 49 岁的人更有可能报告过去或最近使用过大麻。如果患有癌症，年轻患者会觉得大麻更容易获得，风险更小。
癌症患者使用大麻的可能性较小，但不同年龄的人对大麻的看法和使用模式不同。在研究大麻和癌症时应考虑年龄因素，可能需要制定政策举措，为癌症患者提供有关大麻风险的高质量信息。
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