Regenerative Medicine and Disability Research (RMDR) Lab, Department of Biomedical Sciences, UIC College of Medicine at Rockford, IL, United States of America.
Department of Civil and Material Engineering, College of Engineering, UIC, Chicago, United States of America.
Mater Sci Eng C Mater Biol Appl. 2021 Jul;126:112128. doi: 10.1016/j.msec.2021.112128. Epub 2021 Apr 26.
According to the National Center for Health Statistics, currently, more than 250,000 total hip replacements annually in the US alone, with an estimated increase to 500,000 by the year 2030. The usage of tapered junctions between the femoral neck and head gives the surgeon flexibility in implant assembly. However, these modular junctions are subjected to micro-motion that may cause chemical and fretting-corrosion at the modular junction. Therefore, it is imperative to study these forces to mitigate their effects. The current study aims to understand the effects of fretting-corrosion as a function of fretting frequencies caused by common physical activities in an in-vitro model of hip modular junctions. The fretting system has a tribological contact condition of flat-on-flat, mounted to a load frame. CoCrMo pins were polished and immersed in a synovial fluid-like electrolyte solution (Bovine calf serum 30 g/l). Electrochemical measurements were made using a potentiostat. Samples then undergo 3600 cycles at 50 μm (to simulate gross slips), with a horizontal load at 200 N, and a frequency of 0.5 Hz, 0.7 Hz, 1 Hz, and 1.5 Hz to simulate Sit Down-Stand Up, Stair Climb, Walking, and Jogging, respectively. Worn surfaces were then examined under optical and scanning electron microscopy. The evolution of free potential as a function of time for tested frequencies shows the initial potential drop and stabilized trend in the potential evolution. The sample group at a higher frequency displays a higher tendency of corrosion than a lower frequency; however, the dissipation energy decreases as a function of fretting frequency. Both electrochemical and mechanical responses correlate to the variation in the fretting frequencies. Organometallic complexes were found on the surfaces of the samples that were subjected to a slower frequency of fretting, whereas mechanical grooving was noticed on samples with a faster frequency. Hence, these preliminary studies suggest that implant failure rates may be altered based on fretting-frequencies induced by physical activity. Further studies will be required to verify the findings and explore the potential role of fretting frequency in the damage modes of the modular junction.
根据美国国家卫生统计中心的数据,目前仅在美国每年就有超过 25 万例全髋关节置换术,预计到 2030 年将增加到 50 万例。股骨颈和头部之间使用锥形连接为外科医生提供了植入物组装的灵活性。然而,这些模块化连接会发生微运动,可能导致模块化连接处发生化学和微动腐蚀。因此,研究这些力以减轻其影响至关重要。本研究旨在了解微动腐蚀的影响,作为在髋关节模块化连接的体外模型中由常见物理活动引起的微动频率的函数。微动系统具有平面对平面的摩擦学接触条件,安装在负载框架上。CoCrMo 销被抛光并浸入类似于滑液的电解质溶液(牛犊血清 30g/l)中。使用电位计进行电化学测量。然后,样品在 50μm 处进行 3600 次循环(模拟总滑移),水平负载为 200N,频率为 0.5Hz、0.7Hz、1Hz 和 1.5Hz,分别模拟坐站、爬楼梯、行走和慢跑。然后在光学和扫描电子显微镜下检查磨损表面。测试频率的自由电位随时间的演变表明初始电位下降和电位演变的稳定趋势。在较高频率下的样品组比在较低频率下显示出更高的腐蚀趋势;然而,耗散能量随微动频率的降低而降低。电化学和机械响应都与微动频率的变化相关。在受到较慢微动频率的样品表面上发现了有机金属配合物,而在受到较快频率的样品上则发现了机械刻槽。因此,这些初步研究表明,植入物的失败率可能会根据物理活动引起的微动频率而改变。需要进一步的研究来验证这些发现,并探索微动频率在模块化连接的损伤模式中的潜在作用。