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吞咽困难和声音嘶哑的不常见病因。

Unusual cause of dysphagia and dysphonia.

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India

Department of Otorhinolaryngology and Head and Neck Surgery, Medanta The Medicity, Gurgaon, Haryana, India.

出版信息

BMJ Case Rep. 2021 Jun 2;14(6):e243060. doi: 10.1136/bcr-2021-243060.

DOI:10.1136/bcr-2021-243060
PMID:34083199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8174514/
Abstract

Forestier's disease is an idiopathic noninflammatory condition associated with enthesopathy leading to hyperostosis of the vertebrae and peripheral skeletal system. The disease tends to affect elderly individuals and remains asymptomatic in most of the cases. Uncommonly, the patient may present with upper aerodigestive symptomatology, usually dysphagia. In elderly individuals, the disease may closely mimic upper aerodigestive tract malignancy, which should be actively excluded. In our patient, the hypopharyngeal soft tissue distortions created by the bony hypertrophy shifted the clinicoradiological suspicion towards malignant pathology. The current case presents the diagnostic dilemma associated with the disease and the need to keep the possibility of severe cervical bony hypertrophy as a cause of upper aerodigestive symptoms in mind.

摘要

Forestier 病是一种特发性非炎症性疾病,与腱末端病相关,导致脊柱和周围骨骼系统骨质增生。该病多见于老年人,多数情况下无症状。不常见的是,患者可能出现上呼吸道症状,通常为吞咽困难。在老年人中,该疾病可能与上呼吸道恶性肿瘤非常相似,因此应积极排除。在我们的患者中,由于骨肥大导致的下咽软组织变形,使临床和影像学怀疑偏向恶性病变。本病例提出了与该疾病相关的诊断难题,并需要注意严重颈椎骨肥大作为上呼吸道症状的原因的可能性。

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Unusual cause of dysphagia and dysphonia.吞咽困难和声音嘶哑的不常见病因。
BMJ Case Rep. 2021 Jun 2;14(6):e243060. doi: 10.1136/bcr-2021-243060.
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本文引用的文献

1
Forestier's disease and its implications in otolaryngology: literature review.Forestier 病及其在耳鼻喉科的意义:文献回顾。
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2
Diffuse idiopathic skeletal hyperostosis (Forestier-Rotes-Querol disease): what's new?弥漫性特发性骨肥厚(Forestier-Rotes-Querol 病):有哪些新进展?
Joint Bone Spine. 2013 Oct;80(5):466-70. doi: 10.1016/j.jbspin.2013.02.011. Epub 2013 Apr 6.
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Serum Dkk-1 levels of DISH patients are not different from healthy controls.
Joint Bone Spine. 2011 Jul;78(4):422-3. doi: 10.1016/j.jbspin.2011.02.015. Epub 2011 Apr 3.
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Anterior cervical osteophyte dysphagia: manofluorographic and functional outcomes after surgery.颈椎前骨赘性吞咽困难:手术后的 manofluorographic 和功能结果。
Head Neck. 2010 May;32(5):588-93. doi: 10.1002/hed.21226.
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Postsurgical recurrence of osteophytes causing dysphagia in patients with diffuse idiopathic skeletal hyperostosis.弥漫性特发性骨肥厚症患者术后骨赘复发导致吞咽困难。
Eur Spine J. 2009 Nov;18(11):1652-8. doi: 10.1007/s00586-009-1133-3.
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The management of dysphasia in skeletal hyperostosis.骨肥厚性骨病中吞咽困难的管理。
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The prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in two large American Midwest metropolitan hospital populations.美国中西部两个大型都市医院人群中弥漫性特发性骨肥厚(DISH)的患病率。
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Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH).弥漫性特发性骨肥厚(DISH)中脊柱受累的影像学和病理学特征。
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